Abstract
Background
The adoption of a second dose of the measles-mumps-rubella (MMR) vaccine among Taiwanese school children began in 2001. However, during that time, mumps cases continued to occur. The purpose of the present study was to assess the epidemiology and vaccination policy for mumps in Taiwan.
Methods
We examined the data on mumps cases collected by the Taiwan Centers for Disease Control (Taiwan CDC) between 2006 and 2011.
Results
During the 6-year study period, a total of 6612 cases of mumps were reported to the Taiwan CDC. Of the patients with known vaccination status, 62% received one dose of the MMR vaccine or no vaccine. The incidence of mumps ranged from 4.18 to 5.28 per 100 000 population and peaked in 2007. Males had a higher incidence of mumps than females (5.9 vs. 3.7 per 100 000 population; P=0.024). Children between 5 and 6 years of age had the highest incidence of mumps, and those 20 years and older had the lowest incidence. Compared to those who received two doses of the MMR vaccine, patients who were not vaccinated or received a single dose of the vaccine had a higher risk of suffering from complications and/or hospitalization.
Conclusions
In Taiwan, more than 60% of mumps cases received either no dose or one dose of the MMR vaccine. Monitoring mumps through biological testing and instituting a second dose of the MMR vaccine for children is needed for the elimination of mumps in Taiwan.
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References
Leinikki P. Mumps. In: Zuckerman AJ, Banatvala JE, Pattison JR, eds. Principles and practice of clinical virology, 4th ed. Chichester: Wiley, 2004:459–466.
Richardson M, Elliman D, Maguire H, Simpson J, Nicoll A. Evidence base of incubation periods, periods of infectiousness and exclusion policies for the control of communicable diseases in schools and preschools. Pediatr Infect Dis J 2001;20:380–391.
Seward J, Strebel P, Robertson S. Mumps. In: Heymann DL, eds. Control of Communicable Diseases Manual, 19th ed. Washington, DC: American Public Health Association, 2008:431–434.
Galazka AM, Robertson SE, Kraigher A. Mumps and mumps vaccine: a global review. Bull World Health Organ 1999;77:3–14.
A retrospective survey of the complications of mumps. J R Coll Gen Pract 1974;24:552–556.
Watson-Creed G, Saunders A, Scott J, Lowe L, Pettipas J, Hatchette TF. Two successive outbreaks of mumps in Nova Scotia among vaccinated adolescents and young adults. CMAJ 2006;175:483–488.
Coffinières E, Turbelin C, Riblier D, Aouba A, Levy-Bruhl D, Arena C, et al. Mumps: burden of disease in France. Vaccine 2012;30:7013–7018.
Centers for Disease Control, Department of Health, Taiwan. Notifiable Infectious Disease Statistical System. http://nidss.cdc.gov.tw (accessed May 14, 2013).
Chang YK, Chen JY, Chang HL, Yu MC, Hsiao HF, Hou CC, et al. Absence of endemic measles transmission in a highly vaccinated population from 1999 to 2008: implications of sustained measles elimination in Taiwan. Vaccine 2010;28:5532–5537.
Chen KT, Chang HL, Wang ST, Cheng YT, Yang JY. Epidemiologic features of hand-foot-mouth disease and herpangina caused by enterovirus 71 in Taiwan, 1998–2005. Pediatrics 2007;120:e244–252.
Tan HF, Yeh CY, Chang HW, Chang CK, Tseng HF. Private doctors’ practices, knowledge, and attitude to reporting of communicable diseases: a national survey in Taiwan. BMC Infect Dis 2009;9:11.
Kidokoro M, Tuul R, Komase K, Nymadawa P. Characterization of mumps viruses circulation in Mongolia: identification of a novel cluster of genotype H. J Clin Microbiol 2011;49:1917–1925.
Dayan GH, Quinlisk MP, Parker AA, Barskey AE, Harris ML, Schwartz JM, et al. Recent resurgence of mumps in the United States. N Engl J Med 2008;358:1580–1589.
Rota JS, Turner JC, Yost-Daljev MK, Freeman M, Toney DM, Meisel E, et al. Investigation of a mumps outbreak among university students with two measles-mumps-rubella (MMR) vaccinations, Virginia, September-December 2006. J Med Virol 2006;81:1819–1825.
Schwarz NG, Bernard H, Melnic A, Bucov V, Caterinciuc N, an der Heiden M, et al. Mumps outbreak in the Republic of Moldova, 2007–2008. Pediatr Infect Dis J 2010;29:703–706.
Parker Fiebelkorn A, Rosen JB, Brown C, Zimmerman CM, Renshowitz H, D’Andrea C, et al. Environmental factors potentially associated with mumps transmission in yeshivas during a mumps outbreak among highly vaccinated students: Brooklyn, New York, 2009–2010. Hum Vaccin Immunother 2013;9:189–194.
National Immigration Agency, Taiwan. Statistics. National Immigration agency, Taipei, Taiwan, 2013. http://www.immigration.gov.tw (accessed January 10, 2013).
Global status of mumps immunization and surveillance. Wkly Epidemiol Rec 2005;80:418–424.
Cortese MM, Jordan HT, Curns AT, Quinlan PA, Ens KA, Denning PM, et al. Mumps vaccine performance among university students during a mumps outbreak. Clin Infect Dis 2008;46:1172–1180.
Date AA, Kyaw MH, Rue AM, Klahn J, Obrecht L, Krohn T, et al. Long-term persistence of mumps antibody after receipt of two MMR vaccination and antibody response after a third MMR vaccination among a university population. J Infect Dis 2008;197:1662–1668.
Rubin SA, Link MA, Sauder CJ, Zhang C, Ngo L, Rima BK, et al. Recent mumps outbreaks in vaccinated populations: no evidence of immune escape. J Virol 2012;86:615–620.
Dayan GH, Rubin S. Mumps outbreaks in vaccinated populations:are available mumps vaccines effective enough to prevent outbreaks? Clin Infect Dis 2008;47:1458–1467.
Bangor-Jones RD, Dowse GK, Giele CM, van Buynder PG, Hodge MM, Whitty MM. A prolonged mumps outbreak among highly vaccinated Aboriginal people in the Kimberley region of Western Australia. Med J Aust 2009;191:398–401.
Akcali A, Yilmaz N, Uyar Y, Ertek M, Buzgan T. Genotyping of mumps virus circulating in Turkey in the 2006–2007 winter season. Arch Virol 2009;154:1807–1812.
Roush SW, Murphy TV; Vaccine-Preventable Disease Table Working Group. Historical comparisons of morbidity and mortality for vaccine-preventable diseases in the United States. JAMA 2007;298:2155–2163.
Cohen C, White JM, Savage EJ, Glynn JR, Choi Y, Andrews N, et al. Vaccine effectiveness estimates, 2004–2005 mumps outbreak, England. Emerg Infect Dis 2007;13:12–17.
Deeks SL, Lim GH, Simpson MA, Gagné L, Gubbay J, Kristjanson E, et al. An assessment of mumps vaccine effectiveness by dose during an outbreak in Canada. CMAJ 2011;183:1014–1020.
Quinlisk MP. Mumps control today. J Infect Dis 2010;202:655–656.
Eriksen J, Davidkin I, Kafatos G, Andrews N, Barbara C, Cohen D, et al. Seroepidemiology of mumps in Europe (1996–2008): why do outbreaks occur in highly vaccinated populations? Epidemiol Infect 2012;12:1–16.
Anderson RM, May RM. Vaccination and herd immunity to infectious diseases. Nature 1985;318:323–329.
Briss PA, Fehrs LJ, Parker RA, Wright PF, Sannella EC, Hutcheson RH, et al. Sustained transmission of mumps in a highly vaccinated population: assessment of primary vaccine failure and waning vaccine-induced immunity. J Infect Dis 1994;169:77–82.
Nelson GE, Aguon A, Valencia E, Oliva R, Guerrero ML, Reyes R, et al. Epidemiology of a mumps outbreak in a highly vaccinated island population and use a third dose of measlesmumps-rubella vaccine for outbreak control-Guam 2009 to 2010. Pediatr Infect Dis J 2013;32:374–380.
Department of Household Registration Affair. Ministry of Interior, R.O.C. National Statistics, R.O.C. (Taiwan). www.ris.gov.tw/ch4/static/st10-0.htm (accessed August 11, 2013).
Wang IJ, Huang LM, Chen HH, Hwang KC, Chen CJ. Seroprevalence of rubella infection after national immunization program in Taiwan: vaccination status and immigration impact. J Med Virol 2007;79:97–103.
World Health Organization. Measles: Mortality reduction and regional elimination plan. WHO, Geneva, 2005.
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Chen, CC., Lu, CC., Su, BH. et al. Epidemiologic features of mumps in Taiwan from 2006 to 2011: a new challenge for public health policy. World J Pediatr 11, 141–147 (2015). https://doi.org/10.1007/s12519-014-0525-6
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DOI: https://doi.org/10.1007/s12519-014-0525-6