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Functionele netwerken; preoperatieve en intraoperatieve mapping van cognitieve functies bij wakkere resectie van (laaggradige) gliomen

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Neuropraxis

Samenvatting

Het doel van glioomchirurgie is een zo maximaal mogelijke resectie, met behoud van cognitief functioneren en daarmee kwaliteit van leven voor de patiënt. Gezien het feit dat gliomen vaak gelegen zijn in zogenoemde eloquente gebieden en vanwege de enorme interindividuele anatomische en functionele variatie, is het van belang om goed geïnformeerd te zijn over de functionele betrokkenheid van hersengebieden die bij deze cognitieve functies betrokken zijn. Het is mogelijk om tijdens een wakkere glioomresectie gebieden te lokaliseren die sensomotorische functies, taal en overige hogere orde cognitieve functies beïnvloeden. Dit kan met preoperatieve functional imaging, in combinatie met intraoperatieve elektrische stimulatie (IES). De informatie die daarmee verkregen wordt, geeft inzicht in de corticale en subcorticale organisatie van functionele netwerken. Dergelijke informatie kan van nut zijn voor het plannen van de (mate) van resectie, selectie van intraoperatieve taken, voorspellen van postoperatief cognitief functioneren en het vroegtijdig plannen van cognitieve revalidatie.

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Authors and Affiliations

  1. Afdeling Neurologie, Universitair Medisch Centrum Groningen, Postbus 30.001, 9700 RB, Groningen, Nederland

    Ingeborg Bosma

  2. Afdeling Neurochirurgie en Afdeling Neurologie – unit Neuropsychologie, Universitair Medisch Centrum Groningen, Groningen, Nederland

    Wencke S. Veenstra

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  1. Ingeborg Bosma
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  2. Wencke S. Veenstra
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Correspondence to Ingeborg Bosma.

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Bosma, I., Veenstra, W.S. Functionele netwerken; preoperatieve en intraoperatieve mapping van cognitieve functies bij wakkere resectie van (laaggradige) gliomen. Neuropraxis 20, 100–107 (2016). https://doi.org/10.1007/s12474-016-0120-9

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