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PS13 - 2. Glycoprotein Nonmetastatic Melanoma protein B (GPNMB) is induced in obese macrophages as a result of lysosomal stress

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Nederlands Tijdschrift voor Diabetologie Aims and scope

Abstract

It has been extensively described that low-grade inflammatory condition plays a crucial role in the genesis and development of diseases in metabolic syndrome. Furthermore, macrophage infiltration in the adipose compartment increases the local level of inflammatory cytokines that cause insulin resistance and inhibition of adipocyte differentiation.

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Authors and Affiliations

  1. http://www.bsl.nl

    Tanit Lizama, Marc Tol, Roelof Ottenhof, Cindy van Roomen, Jan Aten, Nike Claessen, Berend Hooibrink, Carmen Argmann, Leonie van Elsenburg, Johannes M.F.G. Aerts & Marco van Eijk

  2. Endocrinology and Metabolism, AMC, Amsterdam, The Netherlands

    Barbara de Weijer & Mireille J. Serlie

  3. University of Amsterdam, Amsterdam, The Netherlands

    Barbara de Weijer & Mireille J. Serlie

Authors
  1. Tanit Lizama
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  2. Marc Tol
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  3. Roelof Ottenhof
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  4. Cindy van Roomen
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  5. Jan Aten
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  6. Nike Claessen
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  7. Berend Hooibrink
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  8. Barbara de Weijer
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  9. Mireille J. Serlie
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  10. Carmen Argmann
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  11. Leonie van Elsenburg
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  12. Johannes M.F.G. Aerts
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  13. Marco van Eijk
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Corresponding author

Correspondence to Tanit Lizama.

Additional information

Depts. of 1 Medical Biochemistry, 2 Pathology, 3 Cell Biology, 4 Endocrinology and Metabolism, AMC, University of Amsterdam, Amsterdam, The Netherlands. Email: t.l.gabriel@amc.uva.nl

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Lizama, T., Tol, M., Ottenhof, R. et al. PS13 - 2. Glycoprotein Nonmetastatic Melanoma protein B (GPNMB) is induced in obese macrophages as a result of lysosomal stress. NED. TIJDSCHR. DIABET. 11, 172 (2013). https://doi.org/10.1007/s12467-013-0122-7

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  • DOI: https://doi.org/10.1007/s12467-013-0122-7

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