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HPV-vaccinatie

Samenvatting

In 2009 is vaccinatie tegen humaan papillomavirus (HPV) opgenomen in het Nederlandse Rijksvaccinatieprogramma voor 13-jarige meisjes. HPV is een seksueel overdraagbaar virus dat veel voorkomt. De meeste infecties met HPV gaan vanzelf weer over en brengen geen klachten met zich mee. Wanneer het lichaam het virus niet opruimt, kan HPV genitale wratten en kanker veroorzaken. De meest voorkomende vorm van kanker die door HPV wordt veroorzaakt is baarmoederhalskanker. Er zijn momenteel drie verschillende vaccins goedgekeurd voor gebruik in Europa: het bivalente (HPV16/18), het quadrivalente (HPV16/18/6/11) en het nonavalente (HPV16/18/6/11/31/33/45/52/58) vaccin. Alle vaccins laten een goede protectie zien tegen het krijgen van een HPV-infectie, en tegen voorstadia van baarmoederhalskanker. Op grond daarvan verwacht men dat het vaccin op langere termijn ook bescherming biedt tegen het krijgen van baarmoederhalskanker. Het risico op serieuze bijwerkingen is nihil. Het effect van de HPV-vaccinatie op het bevolkingsonderzoek naar baarmoederhalskanker is nog niet bekend. In 2023 zullen de eerste cohorten die gevaccineerd zijn tegen HPV uitgenodigd worden voor deelname aan het bevolkingsonderzoek.

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Correspondence to Inge M. C. M. de Kok.

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de Kok, I.M.C.M., Matthijsse, S.M. HPV-vaccinatie. Bijblijven 33, 29–40 (2017). https://doi.org/10.1007/s12414-016-0200-z

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