Skip to main content
SpringerLink
Log in

Whole-body MRI: huidige stand van zaken en toekomstperspectief

  • Published:
Bijblijven

Samenvatting

Voor de radiologische diagnostiek van (benigne en maligne) multisysteemziekten was men tot voor kort aangewezen op beeldvormende technieken als conventioneel röntgenonderzoek, computertomografie (CT), en nucleair geneeskundige technieken. Tegenwoordig is het mogelijk om met magnetic resonance imaging (MRI) afbeeldingen te maken van het gehele lichaam zonder het gebruik van ioniserende straling, met een hoge beeldkwaliteit en in een voor de patiënt acceptabele scantijd. In deze bijdrage wordt ingegaan op de huidige stand van zaken en (potentiële) toepassingsgebieden van whole-body MRI.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figuur 1
Figuur 2
Figuur 3
Figuur 4
Figuur 5

Literatuur

  1. Chavhan GB, Babyn PS. Whole-body MR imaging in children: principles, technique, current applications, and future directions. Radiographics. 2011;31(6):1757–72.

    Article  PubMed  Google Scholar 

  2. Kwee TC, Takahara T, Ochiai R, Katahira K, Cauteren M van, Imai Y, et al. Whole-body diffusion-weighted magnetic resonance imaging. Eur J Radiol. 2009;70:409–17.

    Article  PubMed  Google Scholar 

  3. Kwee TC, Takahara T, Vermoolen MA, Bierings MB, Mali WP, Nievelstein RA. Whole-body diffusion-weighted imaging for staging malignant lymphoma in children. Pediatr Radiol. 2010;40(10):1592–1602.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Pooley RA. Fundamental physics of MR imaging. Radiographics. 2005;25:1087–99.

    Article  PubMed  Google Scholar 

  5. Jacobs MA, Ibrahim TS, Ouwerkerk R. MR imaging: brief overview and emerging applications. Radiographics. 2007;27:1213–29.

    Article  PubMed  Google Scholar 

  6. Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014;32(27):3059–68.

    Article  PubMed  Google Scholar 

  7. Punwani S, Taylor SA, Bainbridge A, Prakash V, Bandula S, De Vita E, et al. Pediatric and adolescent lymphoma: comparison of whole-body STIR half-Fourier RARE MR imaging with an enhanced PET/CT reference for initial staging. Radiology. 2010;255(1):182–90.

    Article  PubMed  Google Scholar 

  8. Littooij AS, Kwee TC, Barber I, Granata C, Vermoolen MA, Enríquez G, et al. Whole-body MRI for initial staging of paediatric lymphoma: prospective comparison to an FDG-PET/CT-based reference standard. Eur Radiol. 2014;24(5):1153–65.

    Article  PubMed  Google Scholar 

  9. Mayerhoefer ME, Karanikas G, Kletter K, Prosch H, Kiesewetter B, Skrabs C, et al. Evaluation of diffusion-weighted magnetic resonance imaging for follow-up and treatment response assessment of Lymphoma: results of an 18F-FDG-PET/CT-controlled prospective study in 64 patients. Clin Cancer Res. 2015;21(11):2506–13.

    Article  CAS  PubMed  Google Scholar 

  10. Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, et al., INRG Task Force. The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2009;27(2):298–303.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Pfluger T, Schmied C, Porn U, Leinsinger G, Vollmar C, Dresel S, et al. Integrated imaging using MRI and 123I metaiodobenzylguanidine scintigraphy to improve sensitivity and specificity in the diagnosis of pediatric neuroblastoma. AJR Am J Roentgenol. 2003;181(4):1115–24.

    Article  PubMed  Google Scholar 

  12. Padhani AR, Gogbashian A. Bony metastases: assessing response to therapy with whole-body diffusion MRI. Cancer Imaging. 2011;11:S1–S17.

    Article  Google Scholar 

  13. Schmidt G, Dinter D, Reiser MF, Schoenberg SO. The uses and limitations of whole-body magnetic resonance imaging. Dtsch Arztebl Int. 2010;107(22):383–9.

    PubMed  PubMed Central  Google Scholar 

  14. Goo HW, Yang DH, Ra YS, Song JS, Im HJ, Seo JJ, et al. Whole-body MRI of Langerhans cell histiocytosis: comparison with radiography and bone scintigraphy. Pediatr Radiol. 2006;36:1019–31.

    Article  PubMed  Google Scholar 

  15. Steinborn M, Wörtler K, Nathrath M, Schöniger M, Hahn H, Rummeny EJ. Whole-body MRI in children with Langerhans cell histiocytosis for the evaluation of the skeletal system. Rofo. 2008;180:646–53.

    Article  CAS  PubMed  Google Scholar 

  16. Sommer G, Klarhöfer M, Lenz C, Scheffler K, Bongartz G, Winter L. Signal characteristics of focal bone marrow lesions in patients with multiple myeloma using whole body T1w-TSE, T2w-STIR and diffusion-weighted imaging with background suppression. Eur Radiol. 2011;21:857–62.

    Article  PubMed  Google Scholar 

  17. Iyer RS, Thapa MM, Chew FS. Chronic recurrent multifocal osteomyelitis: review. AJR Am J Roentgenol. 2011;196:S87–S91.

    Article  PubMed  Google Scholar 

  18. Costa-Reis P, Sullivan KE. Chronic recurrent multifocal osteomyelitis. J Clin Immunol. 2013;33:1043–56.

    Article  PubMed  Google Scholar 

  19. Royen-Kerkhof A van. Juveniele dermatomyositis: de huidige stand van zaken. Ned Tijdschr Allerg Astma. 2010;10(2):61–8.

    Google Scholar 

  20. Davis WR, Halls JE, Offiah AC, Pilkington C, Owens CM, Rosendahl K. Assessment of active inflammation in juvenile dermatomyositis: a novel magnetic resonance imaging-based scoring system. Rheumatology. 2011;50:2237–44.

    Article  PubMed  Google Scholar 

  21. Ladd PE, Emery KH, Salisbury SR, Laor T, Lovell DJ, Bove KE. Juvenile dermatomyositis: correlation of MRI at presentation with clinical outcome. AJR Am J Roentgenol. 2011;2011(197):W153–8.

    Article  Google Scholar 

  22. Malattia C, Damasio MB, Madeo A, Pistorio A, Providenti A, Pederzoli S, et al. Whole-body MRI in the assessment of disease activity in juvenile dermatomyositis. Ann Rheum Dis. 2014;73:1083–90.

    Article  PubMed  Google Scholar 

  23. Friedman DN, Lis E, Sklar CA, Oeffinger KC, Reppucci M, Fleischut MH, et al. Whole-body magnetic resonance imaging (WB-MRI) as surveillance for subsequent malignancies in survivors of hereditary retinoblastoma: a pilot study. Pediatr Blood Cancer. 2014;61(8):1440–4.

    Article  PubMed  Google Scholar 

  24. Anupindi SA, Bedoya MA, Lindell RB, Rambhatla SJ, Zelley K, Nichols KE, Chauvin NA. Diagnostic performance of whole-body MRI as a tool for cancer screening in children with genetic cancer-predisposing conditions. AJR. Am J Roentgenol. 2015;205:400–8.

    Article  PubMed  Google Scholar 

  25. Hirsch FW, Sattler B, Sorge I, Kurch L, Viehweger A, Ritter L, et al. PET/MR in children. Initial clinical experience in paediatric oncology using an integrated PET/MR scanner. Pediatr Radiol. 2013;43:860–75.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Universitair Medisch Centrum, Utrecht, Nederland

    Rutger A. J. Nievelstein &  Thomas C. Kwee

Authors
  1. Rutger A. J. Nievelstein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Thomas C. Kwee
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rutger A. J. Nievelstein.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nievelstein, R.A.J., Kwee, T.C. Whole-body MRI: huidige stand van zaken en toekomstperspectief. Bijblijven 32, 284–295 (2016). https://doi.org/10.1007/s12414-016-0138-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12414-016-0138-1

Search

Navigation