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De genetische aspecten van obesitas

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Bijblijven

Samenvatting

Obesitas is een van de grootste gezondheidsproblemen in onze huidige maatschappij, met een sterk stijgende prevalentie. Deze stijging is grotendeels toe te schrijven aan externe omgevingsfactoren. Genetisch onderzoek naar obesitas heeft in de afgelopen jaren geresulteerd in de identificatie van causale genen zowel voor syndromale als monogene vormen van obesitas. Tevens kon een aantal genetische risicovarianten worden geïdentificeerd die betrokken zijn bij de multifactoriële vorm van obesitas. Dit alles brengt nieuwe inzichten mee in het ontstaansmechanisme van obesitas en kan de poorten openen naar nieuwe therapeutische behandelingen.

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Authors and Affiliations

  1. Centrum Medische Genetica, Universiteit Antwerpen, Edegem, België

    Wim Van Hul

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  1. Wim Van Hul
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Correspondence to Wim Van Hul.

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Van Hul, W. De genetische aspecten van obesitas. Bijblijven 32, 25–32 (2016). https://doi.org/10.1007/s12414-016-0113-x

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  • DOI: https://doi.org/10.1007/s12414-016-0113-x

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