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Nierinsufficiëntie en medicatie

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Samenvatting

In de huisartsenpraktijk neemt het aantal patiënten met een verminderde nierfunctie toe. Veel geneesmiddelen worden renaal uitgescheiden, wat onder andere consequenties heeft voor de dosering van deze geneesmiddelen. Het is in de dagelijkse praktijk niet altijd gemakkelijk hiermee om te gaan. In deze bijdrage gaan we dieper in op de beoordeling van de nierfunctie en geven we vervolgens achtergrondinformatie en praktische adviezen omtrent het gebruik van antibiotica, orale antidiabetica, ACE-remmers, NSAID’s, diuretica en de nieuwe directe orale anticoagulantia (DOAC) bij nierinsufficiëntie.

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internist in opleiding – klinisch farmacoloog in opleiding, Radboudumc, Nijmegen

huisarts en hoofd Eerstelijnsvervolgopleidingen, Radboudumc Nijmegen

internist-klinisch farmacoloog, Canisius-Wilhelmina ziekenhuis en Radboudumc, Nijmegen

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Esselink, A., Scherpbier-de Haan, N. & Kramers, K. Nierinsufficiëntie en medicatie. Bijblijven 30, 54–60 (2014). https://doi.org/10.1007/s12414-014-0024-7

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