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Present Status and Future Direction of NIRS-IVUS Multimodality Direct Coronary Imaging

  • Intravascular Imaging (I.-K. Jang, Section Editor)
  • Published:
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Abstract

Intracoronary near-infrared spectroscopy (NIRS)-IVUS is a direct coronary imaging catheter for the identification and quantification of lipid core plaque (LCP). NIRS is combined with traditional grayscale IVUS in a hybrid catheter that provides co-registered architectural and compositional plaque characterization data. The novel capability of the NIRS catheter component is its ability to directly identify LCP, which underlies the majority of vulnerable and unstable plaques. NIRS-IVUS has potential to optimize percutaneous coronary intervention (PCI) by delineating precise lesion length, assuring adequate stent expansion and apposition, detection of stent edge dissection, and predicting periprocedural myocardial infarction (PMI). NIRS-IVUS may also be important in the identification of vulnerable plaques at risk to cause future events.

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Conflict of Interest

JA Goldstein has served as a consultant, received travel reimbursement, and owns stock in InfraReDx, Inc. JE Muller has served as Chairman of the Board and Chief Medical Officer, received travel reimbursement, and owns stock in InfraReDx, Inc. ID Hanson, SR Dixon, AE Abbas, and RD Safian all declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Cardiovascular Medicine, Beaumont Health System, 3601 West 13 Mile Road, Royal Oak, MI, 48073, USA

    Ivan D. Hanson, James A. Goldstein, Simon R. Dixon, Amr E. Abbas & Robert D. Safian

  2. InfraReDx, Inc., Burlington, MA, USA

    James E. Muller

Authors
  1. Ivan D. Hanson
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  2. James A. Goldstein
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  3. Simon R. Dixon
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  4. Amr E. Abbas
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  5. Robert D. Safian
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  6. James E. Muller
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Corresponding author

Correspondence to James A. Goldstein.

Additional information

James A. Goldstein, M.D. is a consultant for and owner of equity in InfraReDx, Inc.

James E. Muller is a current employee of InfraReDx, Inc.

This article is part of the Topical Collection on Intravascular Imaging

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Hanson, I.D., Goldstein, J.A., Dixon, S.R. et al. Present Status and Future Direction of NIRS-IVUS Multimodality Direct Coronary Imaging. Curr Cardiovasc Imaging Rep 8, 25 (2015). https://doi.org/10.1007/s12410-015-9342-0

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  • DOI: https://doi.org/10.1007/s12410-015-9342-0

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