Skip to main content

Advertisement

Log in

New Software Solutions for Cardiac SPECT Imaging

  • Cardiac Nuclear Imaging (A Cuocolo, Section Editor)
  • Published:
Current Cardiovascular Imaging Reports Aims and scope Submit manuscript

Abstract

Recent advances in myocardial perfusion single photon emission computed tomography (SPECT) processing software, incorporating iterative reconstruction, resolution recovery, and noise compensation, now provide the ability to acquire high quality scans despite reduced administered activity, shortened acquisition time, or both. These methods have thereby provided imaging protocol flexibility and facilitated patient-centered imaging. Other software methods allow for improved image quality by prescribing an image acquisition time that will yield optimal SPECT image count density. On some new solid state cameras list mode acquisition is now available, whereby suboptimal acquisition stops such as those with patient motion can be eliminated prior to SPECT reconstruction. Still other methods, incorporating phase analysis of gated perfusion SPECT, provide a quantitative analysis of left ventricular dyssynchrony, aiding in the selection of patients for whom cardiac resynchronization therapy is most beneficial.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Patton JA, Slomka PJ, Germano G, Berman DS. Recent technological advances in nuclear cardiology. J Nucl Cardiol. 2007;14:501–13.

    Article  PubMed  Google Scholar 

  2. • Garcia EV, Faber TL. New trends in camera and software technology in nuclear cardiology. Cardiol Clin. 2009;27:227–36. This review article explains the theory and implementation of new scintillation cameras for myocardial perfusion SPECT and the introduction of new software methods for SPECT reconstruction.

    Article  PubMed  Google Scholar 

  3. DePuey EG. New software methods to cope with reduced counting statistics: shorter SPECT acquisitions and many more possibilities. J Nucl Cardiol. 2009;16:335–8.

    Article  PubMed  Google Scholar 

  4. •• DePuey EG. Advances in SPECT camera software and hardware: currently available and new on the horizon. J Nucl Cardiol. 2012;19:551–81. This review article provides an in-depth explanation of new myocardial perfusion SPECT hardware and software methods and recent clinical results.

    Article  PubMed  Google Scholar 

  5. Metz CE. The geometric transfer function component for scintillation camera collimators with straight parallel holes. Phys Med Biol. 1980;25:1059–70.

    Article  PubMed  CAS  Google Scholar 

  6. Tsui BMW, Gullberg GT. The geometric transfer-function for cone and fan beam collimators. Phys Med Biol. 1990;35:81–93.

    Article  PubMed  CAS  Google Scholar 

  7. Tsui BMW, Hu HB, Gillard DR, Gullberg GT. Implementation of simultaneous attenuation and detector response correction in SPECT. IEEE Trans Nucl Sci. 1988;35:778–83.

    Article  CAS  Google Scholar 

  8. Tsui BMW, Frey EC, Zhao X, Lalush DS, Johnston RE, McCartney WH. The importance and implementation of accurate 3-dimensional compensation methods for quantitative SPECT. Phys Med Biol. 1994;39:509–30.

    Article  PubMed  CAS  Google Scholar 

  9. Tsui BMW, Zhao XD, Frey EC, Gullberg GT. Characteristics of reconstructed point response in 3-dimensional spatially variant detector response compensation in SPECT. In: Grangeat P, Amans J-L, editors. Three-dimensional image reconstruction in radiology and nuclear medicine. Kluwer. Dordrecht: Academic Publishers; 1996. p. 509–30.

  10. Borges-Neto S, Pagnanelli RA, Shaw LK, Honeycutt E, Shwartz SC, Adams GL, et al. Clinical results of a novel wide beam reconstruction method for shortenings can time of Tc-99m cardiac SPECT perfusion studies. J Nucl Cardiol. 2007;14:555–65.

    Article  PubMed  Google Scholar 

  11. Venero CV, Heller GV, Bateman TM, McGhie AI, Ahlberg AW, Katten D, et al. A multicenter evaluation of a new postprocessing method with depth-dependent collimator resolution applied to full-time and half-time acquisitions without and with simultaneously acquired attenuation correction. J Nucl Cardiol. 2009;16:714–25.

    Article  PubMed  Google Scholar 

  12. DePuey EG, Gadiraju R, Clark J, Thompson L, Anstett F, Shwartz SC. Ordered subset expectation that maximization and wide beam reconstruction "half-time" gated myocardial perfusion SPECT functional imaging: a comparison with "full-time" filtered backprojection. J Nucl Cardiol. 2008;15:547–63.

    Article  PubMed  Google Scholar 

  13. DePuey EG, Bommireddipalli S, Clark J, Thompson L, Srour Y. Wide beam reconstruction “quarter-time” gated myocardial perfusion SPECT functional imaging: a comparison with “full-time” ordered subset expectation maximum. J Nucl Cardiol. 2009;16:736–52.

    Article  PubMed  Google Scholar 

  14. DePuey EG, Bommireddipalli S, Clark J, Leykekhman A, Thompson LB, Friedman M. A comparison of the image quality of full-time myocardial perfusion SPECT vs wide beam reconstruction half-time and half-dose SPECT. J Nucl Cardiol. 2011;18:273–80.

    Article  PubMed  Google Scholar 

  15. Chen J, Garcia EV, Folks RD, Cooke CD, Faber TL, Tauxe L, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol. 2005;12:687–95.

    Article  PubMed  Google Scholar 

  16. Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, et al. Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? J Nucl Med. 2007;48:1104–11.

    Article  PubMed  Google Scholar 

  17. Esteves FP, Raggi P, Folks RD, Keidar Z, Askew W, Rispler S, et al. Novel solid- state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras. J Nucl Cardiol. 2009;16:927–34.

    Article  PubMed  Google Scholar 

  18. Erlandsson K, Kacperski K, Van Gramberg D, Hutton B. Performance evaluation of D-SPECT: a novel dedicated cardiac SPECT scanner. Phys Med Biol. 2009;54:2635–2649.

    Article  PubMed  Google Scholar 

  19. Hutton B, Erlandsson K, Kacperski K, Van Gramberg D, Roth N. Performance evaluation of D-SPCT: a novel dedicated cardiac SPECT scanner. J Nucl Med. 2008;49 Suppl 1:124P.

    Google Scholar 

  20. Sharir T, Ben-Haim S, Merzon K, Prochorov V, Dickman D, Ben-Haim S, et al. High-speed myocardial perfusion imaging: initial clinical comparison with conventional dual detector anger camera imaging. J Am Coll Cardiol Imaging. 2008;1:156–63.

    Article  Google Scholar 

  21. Sharir T, Slomka PJ, Hayes SW, DiCarli MF, Ziffer JA, Martin WH, et al. Multicenter trial of high-speed vs conventional single-photon emission computed tomography imaging: quantitative of myocardial perfusion and left ventricular function. J Am Coll Cardiol. 2010;55:1965–74.

    Article  PubMed  Google Scholar 

  22. Corbett J, Meden J, Ficaro E. Clinical validation of attenuation corrected cardiac imaging with IQ-SPECT/CT [abstract]. J Nucl Med. 2010;4(Suppl):733.

    Google Scholar 

  23. Maddahi J, Mendez R, Mahmarian J, Thomas G, Bai C, Babla H, et al. Prospective multicenter evaluation of rapid gated SPECT myocardial perfusion and upright imaging. J Nucl Cardiol. 2009;16:351–7.

    Article  PubMed  Google Scholar 

  24. Duvall WL, Croft LB, Godiwala T, Ginsberg E, George T, Henzlova MJ. Reduced isotope dose with rapid SPECT MPI imaging: Initial experience with a CZT SPECT camera. J Nucl Cardiol. 2010;17:1009–14.

    Article  PubMed  Google Scholar 

Download references

Conflict of Interest

E. Gordon DePuey has been a consultant to UltraSPECT Ltd.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to E. Gordon DePuey.

Rights and permissions

Reprints and permissions

About this article

Cite this article

DePuey, E.G. New Software Solutions for Cardiac SPECT Imaging. Curr Cardiovasc Imaging Rep 6, 314–321 (2013). https://doi.org/10.1007/s12410-013-9204-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12410-013-9204-6

Keywords

Navigation