Abstract
Attention-deficit/hyperactivity disorder (ADHD) has been shown to continue into old age. Studies in children and younger adults show a reduction in hyperactive-impulsive symptoms, whereas the number of inattentive symptoms stays stable. The current study examined the lifetime stability of ADHD symptoms up to old age. Data on ADHD diagnosis and symptoms were collected in a two-phase side-study (N = 231) of the Longitudinal Aging Study Amsterdam. Paired t tests and ANCOVAs were used to analyze the data. Paired t test suggests continuity of the number of reported ADHD symptoms currently present and present in childhood. The change in the balance of inattentive/hyperactive-impulsive symptoms at present and in childhood is also the same in persons with ADHD. Finally, the difference in the change in the balance of inattentive/hyperactive-impulsive symptoms in those with and without ADHD suggests continuity throughout the life span. Our results suggest that diagnostic criteria developed for younger adults may be used among older adults. However, we collected our data retrospectively, which may have biased our results. Future research should follow larger cohorts of patients with ADHD prospectively over the life span.
Similar content being viewed by others
References
American Psychiatric Association (2001) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Publishing, Washington, DC
American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing, Arlington
Barkley RA (1997) Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 121:65e94
Barkley RA, Guevremont DC, Anastopoulos AD, DuPaul GJ, Shelton TL (1993) Driving-related risks and outcomes of attention deficit hyperactivity disorder in adolescents and young adults: a 3-to 5-year follow-up survey. Pediatrics 92:212–218
Barkley RA, Fischer M, Smallish L, Fletcher K (2002) The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder. J Abnorm Psychol 111:279–289
Barkley RA, Murphy KR, Fischer M (2008) ADHD in adults: what the science says. The Guilford Press, New York
Biederman J, Mick E, Faraone SV (2000) Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. Am J Psychiatry 157:816–818
Biederman J, Monuteaux MC, Mick E et al (2006) Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up study. Psychol Med 36:167–179. doi:10.1017/S0033291705006410
Biederman J, Petty CR, Evans M et al (2010) How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD. Psychiatry Res 177:299–304. doi:10.1016/j.psychres.2009.12.010
Dalsgaard S, Østergaard SD, Leckman JF et al (2015) Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort study. The Lancet. doi:10.1016/S0140-6736(14)61684-6
Dias G, Mattos P, Coutinho G et al (2008) Agreement rates between parent and self-report on past ADHD symptoms in an adult clinical sample. J Atten Disord 12:70–75. doi:10.1177/1087054707311221
Faraone SV, Biederman J, Mick E (2006) The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med 36:159–165. doi:10.1017/S003329170500471X
Glisky EL (2007) Changes in Cognitive Function in Human Aging. Brain aging: models, methods, and mechanisms, 1st edn. CRC Press, Boca Raton, pp 3–20
Guldberg-Kjär T, Sehlin S, Johansson B (2013) ADHD symptoms across the lifespan in a population-based Swedish sample aged 65 to 80. Int Psychogeriatr 25:667–675. doi:10.1017/S1041610212002050
Hart EL, Lahey BB, Loeber R et al (1995) Developmental change in attention-deficit hyperactivity disorder in boys: a four-year longitudinal study. J Abnorm Child Psychol 23:729–749
Huisman M, Poppelaars J, van der Horst M et al (2011) Cohort profile: the longitudinal aging study Amsterdam. Int J Epidemiol 40:868–876. doi:10.1093/ije/dyq219
Kooij JJS (2013) Adult ADHD. Diagnostic assessment and treatment, 3rd edn. Springer, London
Kooij JJS, Buitelaar JK, van den Oord EJ et al (2005) Internal and external validity of attention-deficit hyperactivity disorder in a population-based sample of adults. Psychol Med 35:817–827. doi:10.1017/S003329170400337X
Leibson CL, Katusic SK, Barbaresi WJ, Ransom J, O’Brien PC (2001) Use and costs of medical care for children and adolescents with and without attention-deficit/hyperactivity disorder. JAMA 285:60–66
Loeber R, Green SM, Lahey BB, Stouthamer-Loeber M (1991) Differences and similarities between children, mothers, and teachers as informants on disruptive child behavior. J Abnorm Child Psychol 19:75–95. doi:10.1007/BF00910566
Mannuzza S (2002) Accuracy of adult recall of childhood attention deficit hyperactivity disorder. Am J Psychiatry 159:1882–1888. doi:10.1176/appi.ajp.159.11.1882
Michielsen M, Semeijn E, Comijs HC et al (2012) Prevalence of attention-deficit hyperactivity disorder in older adults in The Netherlands. Br J Psychiatry 201:298–305. doi:10.1192/bjp.bp.111.101196
Polanczyk G, Rohde LA (2007) Epidemiology of attention-deficit/hyperactivity disorder across the lifespan. Curr Opin Psychiatry 20:386–392. doi:10.1097/YCO.0b013e3281568d7a
Semeijn EJ, Michielsen M, Comijs HC et al (2013) Criterion validity of an attention deficit hyperactivity disorder (ADHD) screening list for screening ADHD in older adults aged 60–94 years. Am J Geriatr Psychiatry. doi:10.1016/j.jagp.2012.08.003
Sobanski E (2006) Psychiatric comorbidity in adults with attention-deficit/hyperactivity disorder (ADHD). Eur Arch Psychiatry Clin Neurosci 256(Suppl1):i26–i31
Weyandt LL, Iwaszuk W, Fulton K et al (2003) The internal restlessness scale: performance of college students with and without ADHD. J Learn Disabil 36:382–389. doi:10.1177/00222194030360040801
Zucker M, Morris MK, Ingram SM et al (2002) Concordance of self- and informant ratings of adults’ current and childhood attention-deficit/hyperactivity disorder symptoms. Psychol Assess 14:379–389. doi:10.1037//1040-3590.14.4.379
Acknowledgments
Sandra Kooij has received unrestricted research grants from Janssen-Cilag and Shire for this study. Aartjan Beekman has received grants for research from Eli Lilly, Astra Zeneca, Janssen and Shire and as a speaker from Lundbeck and Eli Lilly. The funding organizations had no role in the writing of this research manuscript.
Conflict of interest
Sandra Kooij has been a speaker for Eli Lilly, Janssen and Shire and has received unrestricted research grants from Janssen-Cilag and Shire for this study. Aartjan Beekman has received grants for research from Eli Lilly, Astra Zeneca, Janssen and Shire and as a speaker from Lundbeck and Eli Lilly. The other authors have reported to have no competing interests.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Semeijn, E.J., Comijs, H.C., de Vet, H.C.W. et al. Lifetime stability of ADHD symptoms in older adults. ADHD Atten Def Hyp Disord 8, 13–20 (2016). https://doi.org/10.1007/s12402-015-0178-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12402-015-0178-x