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Killing two birds with one stone: How do Plant Viruses Break Down Plant Defenses and Manipulate Cellular Processes to Replicate Themselves?
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  • Published: 27 May 2019

Killing two birds with one stone: How do Plant Viruses Break Down Plant Defenses and Manipulate Cellular Processes to Replicate Themselves?

  • Pedro Filho Noronha Souza1,2 na1 &
  • Fabricio Eulálio Leite Carvalho1 na1 

Journal of Plant Biology volume 62, pages 170–180 (2019)Cite this article

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Abstract

As simple organisms with a parasite nature, viruses have become masters in manipulating and subvert cellular components, including host proteins and organelles, to improve viral replication. Therefore, the understanding of viral strategies to manipulate cell function disrupting plant defenses and enhancing viral infection cycles is fundamental to the production of virus-resistant plant lines. After invading susceptible plants, viruses create conditions that favor local and systemic infections by suppressing multiple layers of innate host defenses while use cellular machinery to own benefit. Viral interference in interlinked essential cellular functions results in phenotypic changes and disease symptoms, which debilitates plants favoring infection establishment. Herein in this review, the novelty it will be the discussion about the strategies used by (+) single strand RNA viruses to affect cellular processes and components to improve viral replication, in parallel to overcome plant defenses, favoring disease establishment by applying in one action using the same viral protein to coordinate viral replication and breaking down plant defense. This focus on plant-virus interaction was never done before, and this knowledge has the potential to help in the development of new strategies to produce resistant plants.

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  1. These authors contribute equally to this work.

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Center of Science, Federal University of Ceara, Fortaleza, Ceara, Brazil

    Pedro Filho Noronha Souza & Fabricio Eulálio Leite Carvalho

  2. Nebraska Center for Virology, Department of Plant Pathology, University of Nebraska Lincoln, Lincoln, Nebraska, USA

    Pedro Filho Noronha Souza

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  1. Pedro Filho Noronha Souza
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  2. Fabricio Eulálio Leite Carvalho
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Correspondence to Pedro Filho Noronha Souza.

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Souza, P.F.N., Carvalho, F.E.L. Killing two birds with one stone: How do Plant Viruses Break Down Plant Defenses and Manipulate Cellular Processes to Replicate Themselves?. J. Plant Biol. 62, 170–180 (2019). https://doi.org/10.1007/s12374-019-0056-8

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  • Received: 19 February 2019

  • Accepted: 15 March 2019

  • Published: 27 May 2019

  • Issue Date: June 2019

  • DOI: https://doi.org/10.1007/s12374-019-0056-8

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Keywords

  • Cellular manipulation
  • Plant defense
  • Plant host proteins
  • Plant viruses
  • (+) RNA viruses
  • Viral replication
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