Cardiovascular disease in the literature: A selection of recent original research papers
PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock.N Engl J Med.2017;377:2419-32.
Background: The effect of revascularization of the non-culprit coronary artery vessel has been extensively studied in patients with ST elevation myocardial infarction but with limited data among those with concomitant cardiogenic shock. Thiele et al., from the Leipzig Heart Center, randomly assigned patients with acute myocardial infarction, cardiogenic shock and multivessel disease to either a percutaneous revascularization of the culprit lesion only (with the option of staged revascularization of non-culprit lesions) (N = 344), or immediate multivessel revascularization (N = 342). The primary end point was a composite of death or severe renal failure leading to renal-replacement therapy within 30 days after randomization.
Findings: The composite primary end point was significantly lower at 30 days in the culprit-lesion-only PCI group [relative risk, 0.83 (0.71-0.96), P = ....
The authors declare that they have no conflicts of interest.