Journal of Nuclear Cardiology

, Volume 25, Issue 2, pp 665–670 | Cite as

Technical aspects of acquiring and measuring myocardial blood flow: Method, technique, and QA

  • John R. Votaw
  • René R. Sevag Packard
Technologist Corner


Measuring absolute myocardial blood flow (MBF) is becoming a common aid for diagnosing patients suspected to have coronary artery disease. An MBF study, however, requires a scanner with high count rate capability, is more susceptible to artifacts, and is much more technically involved than static imaging, which leads to a greater risk of artifactual results contaminating the final result. This technical note gives the reader an introductory understanding of the method for calculating MBF. It then describes the scanning protocol, potential pitfalls and how to recognize them, and quality control steps that should be taken to avoid basing a clinical decision on possibly inaccurate flow information.


PET Image quality Coronary flow reserve Coronary blood flow 



Myocardial blood flow


Bismuth germanate


Lutetium oxyorthosilicate


Lutetium-yttrium oxyorthosilicate


Gadolinium oxyorthosilicate


Region of interest


Time activity curve(s)


Quality control



John R. Votaw has received consulting fees from Syntermed, Inc. René R. Sevag Packard reports no potential conflicts of interest.


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Copyright information

© American Society of Nuclear Cardiology 2017

Authors and Affiliations

  1. 1.Department of Radiology and Imaging SciencesEmory UniversityAtlantaUSA
  2. 2.Division of Cardiology, Department of MedicineDavid Geffen School of Medicine, University of CaliforniaLos AngelesUSA
  3. 3.Ronald Reagan UCLA Medical CenterLos AngelesUSA
  4. 4.Veterans Affairs West Los Angeles Medical CenterLos AngelesUSA

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