Technical aspects of acquiring and measuring myocardial blood flow: Method, technique, and QA
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Measuring absolute myocardial blood flow (MBF) is becoming a common aid for diagnosing patients suspected to have coronary artery disease. An MBF study, however, requires a scanner with high count rate capability, is more susceptible to artifacts, and is much more technically involved than static imaging, which leads to a greater risk of artifactual results contaminating the final result. This technical note gives the reader an introductory understanding of the method for calculating MBF. It then describes the scanning protocol, potential pitfalls and how to recognize them, and quality control steps that should be taken to avoid basing a clinical decision on possibly inaccurate flow information.
KeywordsPET Image quality Coronary flow reserve Coronary blood flow
Myocardial blood flow
Region of interest
Time activity curve(s)
John R. Votaw has received consulting fees from Syntermed, Inc. René R. Sevag Packard reports no potential conflicts of interest.
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