Skip to main content
SpringerLink
Log in

Assessment of asynchrony by gated myocardial perfusion imaging improves patient management: Pro

  • Debate Article
  • Published:
Journal of Nuclear Cardiology Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Chen J, Garcia EV, Folks RD, Cooke CD, Faber TL, Tauxe EL, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: Development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol. 2005;12:687-95.

    Article  PubMed  Google Scholar 

  2. Tavares A, Peclat T, Lima RS. Prevalence and predictors of left intraventricular dyssynchrony determined by phase analysis in patients undergoing gated SPECT myocardial perfusion imaging. Int J Cardiovasc Imaging. 2016;32:845-52.

    Article  PubMed  Google Scholar 

  3. Boogers MJ, Chen J, Veltman CE, van Bommel RJ, Mooyaart EA, Al Younis I, et al. Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging. Eur J Nucl Med Mol Imaging. 2011;38:2031-9.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Hsu TH, Huang WS, Chen CC, Hung GU, Chen TC, Kao CH, et al. Left ventricular systolic and diastolic dyssynchrony assessed by phase analysis of gated SPECT myocardial perfusion imaging: a comparison with speckle tracking echocardiography. Ann Nucl Med. 2013;27:764-71.

    Article  PubMed  Google Scholar 

  5. Petretta M, Acampa W, Daniele S, Petretta MP, Plaitano M, Cuocolo A. Transient ischemic dilation in patients with diabetes mellitus: prognostic value and effect on clinical outcome after coronary revascularization. Circ Cardiovasc Imaging. 2013;6:908-15.

    Article  PubMed  Google Scholar 

  6. Daniele S, Nappi C, Acampa W, Storto G, Pellegrino T, Ricci F, et al. Incremental prognostic value of coronary flow reserve assessed with single-photon emission computed tomography. J Nucl Cardiol. 2011;18:612-9.

    Article  PubMed  Google Scholar 

  7. Pazhenkottil AP, Buechel RR, Husmann L, Nkoulou RN, Wolfrum M, Ghadri JR, et al. Long-term prognostic value of left ventricular dyssynchrony assessment by phase analysis from myocardial perfusion imaging. Heart. 2011;97:33-7.

    Article  PubMed  Google Scholar 

  8. Chen J, Kalogeropoulos AP, Verdes L, Butler J, Garcia EV. Left ventricular systolic and diastolic dyssynchrony as assessed by multi-harmonic phase analysis of gated SPECT myocardial perfusion imaging in patients with end-stage renal disease and normal LVEF. J Nucl Cardiol. 2011;18:299-308.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Cho SG, Jabin Z, Park KS, Kim J, Kang SR, Kwon SY, et al. Clinical values of left ventricular mechanical dyssynchrony assessment by gated myocardial perfusion SPECT in patients with acute myocardial infarction and multivessel disease. Eur J Nucl Med Mol Imaging. 2017;44:259-66.

    Article  PubMed  Google Scholar 

  10. Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, et al. Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? J Nucl Med. 2007;48:1104-11.

    Article  PubMed  Google Scholar 

  11. Boogers MM, Van Kriekinge SD, Henneman MM, Ypenburg C, Van Bommel RJ, Boersma E, et al. Quantitative gated SPECT-derived phase analysis on gated myocardial perfusion SPECT detects left ventricular dyssynchrony and predicts response to cardiac resynchronization therapy. J Nucl Med. 2009;50(5):718–25. doi:10.2967/jnumed.108.060657.

    Article  PubMed  Google Scholar 

  12. Mukherjee A, Patel CD, Naik N, Sharma G, Roy A. Quantitative assessment of cardiac mechanical dyssynchrony and prediction of response to cardiac resynchronization therapy in patients with nonischaemic dilated cardiomyopathy using gated myocardial perfusion SPECT. Nucl Med Commun. 2015;36:494-501.

    PubMed  Google Scholar 

  13. Boogers MJ, Chen J, van Bommel RJ, Borleffs CJ, Dibbets-Schneider P, van der Hiel B, et al. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Eur J Nucl Med Mol Imaging. 2011;38:230-8.

    Article  PubMed  Google Scholar 

  14. Friehling M, Chen J, Saba S, Bazaz R, Schwartzman D, Adelstein EC, et al. A prospective pilot study to evaluate the relationship between acute change in left ventricular synchrony after cardiac resynchronization therapy and patient outcome using a single-injection gated SPECT protocol. Circ Cardiovasc Imaging. 2011;4(5):532-9.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Lin X, Xu H, Zhao X, Chen J. Sites of latest mechanical activation as assessed by SPECT myocardial perfusion imaging in ischemic and dilated cardiomyopathy patients with LBBB. Eur J Nucl Med Mol Imaging. 2014;41:1232-9.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Schuster I, Habib G, Jego C, Thuny F, Avierinos JF, Derumeaux G, et al. Diastolic asynchrony is more frequent than systolic asynchrony in dilated cardiomyopathy and is less improved by cardiac resynchronization therapy. J Am Coll Cardiol. 2005;46:2250-7.

    Article  PubMed  Google Scholar 

  17. Zafrir N, Bental T, Strasberg B, Solodky A, Mats I, Gutstein A, et al. Yield of left ventricular dyssynchrony by gated SPECT MPI in patients with heart failure prior to implantable cardioverter-defibrillator or cardiac resynchronization therapy with a defibrillator: Characteristics and prediction of cardiac outcome. J Nucl Cardiol. 2017;24:122-9.

    Article  PubMed  Google Scholar 

  18. Hage FG, Aggarwal H, Patel K, Chen J, Jacobson AF, Heo J, et al. The relationship of left ventricular mechanical dyssynchrony and cardiac sympathetic denervation to potential sudden cardiac death events in systolic heart failure. J Nucl Cardiol. 2014;21:78-85. doi:10.1007/s12350-013-9807-y.

    Article  PubMed  Google Scholar 

  19. Hou PN, Tsai SC, Lin WY, Cheng CM, Chiang KF, Chang YC, et al. Relationship of quantitative parameters of myocardial perfusion SPECT and ventricular arrhythmia in patients receiving cardiac resynchronization therapy. Ann Nucl Med. 2015;29:772-8.

    Article  PubMed  Google Scholar 

  20. Folks RD, Cooke CD, Garcia EV. Optimizing gated myocardial perfusion imaging processing for phase analysis. J Nucl Cardiol. 2016;23:1348-54.

    Article  PubMed  Google Scholar 

Download references

Disclosure

The authors have indicated that they have no financial conflict of interest.

Author information

Authors and Affiliations

  1. Department of Translational Medical Sciences, University Federico II, Naples, Italy

    Mario Petretta MD

  2. Department of Arrhythmology, Maria Cecilia Hospital, GVM Care and Research, Cotignola, Italy

    Andrea Petretta MD, PhD

  3. Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy

    Alberto Cuocolo MD

Authors
  1. Mario Petretta MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andrea Petretta MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Alberto Cuocolo MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alberto Cuocolo MD.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Petretta, M., Petretta, A. & Cuocolo, A. Assessment of asynchrony by gated myocardial perfusion imaging improves patient management: Pro. J. Nucl. Cardiol. 25, 532–535 (2018). https://doi.org/10.1007/s12350-017-1021-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12350-017-1021-x

Keywords

Search

Navigation