Skip to main content

Advertisement

Log in

Review of cardiovascular imaging in the journal of nuclear cardiology in 2016: Part 2 of 2—myocardial perfusion imaging

  • Review Article
  • Published:
Journal of Nuclear Cardiology Aims and scope

Abstract

In 2016, the Journal of Nuclear Cardiology published many high-quality articles. Similar to previous years, we will summarize here a selection of the articles that were published in the Journal in 2016 to provide a concise review of the main advancements that have recently occurred in the field. In the first article of this two-part series we focused on publications dealing with positron emission tomography, computed tomography, and magnetic resonance. This review will place emphasis on myocardial perfusion imaging using single-photon emission-computed tomography summarizing advances in the field including in diagnosis, prognosis, and appropriate use.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

Abbreviations

AUC:

Appropriate use criteria

CAD:

Coronary artery disease

CCTA:

Coronary-computed tomography

CZT:

Cadmium-zinc-telluride

DTS:

Duke Treadmill Score

LAD:

Left anterior descending

LVEF:

Left ventricular ejection fraction

MI:

Myocardial infarction

MPI:

Myocardial perfusion imaging

TID:

Transient ischemic dilation

References

  1. AlJaroudi WA, Hage FG. Review of cardiovascular imaging in the journal of nuclear cardiology in 2016. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance. J Nucl Cardiol 2017. doi:10.1007/s12350-017-0820-4.

    Article  PubMed  Google Scholar 

  2. AlJaroudi WA, Hage FG. Review of cardiovascular imaging in the journal of nuclear cardiology in 2014: Part 1 of 2: Positron emission tomography, computed tomography, and neuronal imaging. J Nucl Cardiol 2015;22:507-12.

    Article  Google Scholar 

  3. Hage FG, AlJaroudi WA. Review of cardiovascular imaging in the journal of nuclear cardiology in 2014: Part 2 of 2: Myocardial perfusion imaging. J Nucl Cardiol 2015;22:714-9.

    Article  Google Scholar 

  4. Shaw LJ, Hage FG, Berman DS, Hachamovitch R, Iskandrian A. Prognosis in the era of comparative effectiveness research: Where is nuclear cardiology now and where should it be? J Nucl Cardiol 2012;19:1026-43.

    Article  Google Scholar 

  5. Cantoni V, Green R, Acampa W, Petretta M, Bonaduce D, Salvatore M, et al. Long-term prognostic value of stress myocardial perfusion imaging and coronary computed tomography angiography: A meta-analysis. J Nucl Cardiol 2016;23:185-97.

    Article  Google Scholar 

  6. Naya M, Tamaki N. Stress MPI, coronary CTA, and multimodality for subsequent risk analysis. J Nucl Cardiol 2016;23:198-201.

    Article  Google Scholar 

  7. Oldan JD, Shaw LK, Hofmann P, Phelan M, Nelson J, Pagnanelli R, et al. Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera. J Nucl Cardiol 2016;23:1280-7.

    Article  Google Scholar 

  8. Karimeddini D, Bergmann S. The state of the future is solid. J Nucl Cardiol 2016;23:1288-90.

    Article  Google Scholar 

  9. Poulin MF, Alexander S, Doukky R. Prognostic implications of stress modality on mortality risk and cause of death in patients undergoing office-based SPECT myocardial perfusion imaging. J Nucl Cardiol 2016;23:202-11.

    Article  Google Scholar 

  10. Uretsky S. Beyond ischemia evaluation: The potential for assessing and addressing physical inactivity in the cardiac stress laboratory. J Nucl Cardiol 2016;23:212-4.

    Article  Google Scholar 

  11. Gimelli A, Liga R, Pasanisi EM, Casagranda M, Coceani M, Marzullo P. Influence of cardiac stress protocol on myocardial perfusion imaging accuracy: The role of exercise level on the evaluation of ischemic burden. J Nucl Cardiol 2016;23:1114-22.

    Article  Google Scholar 

  12. Spadafora M, Salvatore M, Cuocolo A. Stress protocol and accuracy of myocardial perfusion imaging: Is it better to start from the end? J Nucl Cardiol 2016;23:1123-7.

    Article  Google Scholar 

  13. Nudi F, Schillaci O, Neri G, Pinto A, Procaccini E, Vetere M, et al. Prognostic impact of location and extent of vessel-related ischemia at myocardial perfusion scintigraphy in patients with or at risk for coronary artery disease. J Nucl Cardiol 2016;23:274-84.

    Article  Google Scholar 

  14. Elhendy A. Prognostic significance of ischemia location on stress myocardial perfusion SPECT: Tracing the fingerprints of the widow maker. J Nucl Cardiol 2016;23:285-6.

    Article  Google Scholar 

  15. El-Hajj S, AlJaroudi WA, Farag A, Bleich S, Manaoragada P, Iskandrian AE, et al. Effect of changes in perfusion defect size during serial regadenoson myocardial perfusion imaging on cardiovascular outcomes in high-risk patients. J Nucl Cardiol 2016;23:101-12.

    Article  Google Scholar 

  16. Iskandrian AE, Roth CP, Hage FG. Serial imaging and outcome prediction. J Nucl Cardiol 2016;23:117-21.

    Article  Google Scholar 

  17. Petretta M, Salvatore M, Cuocolo A. Immortality time and serial myocardial perfusion imaging: Only those who do not die may repeat the exam. J Nucl Cardiol 2016;23:113-6.

    Article  Google Scholar 

  18. Iskandrian AE, Hage FG, Shaw LJ, Mahmarian JJ, Berman DS. Serial myocardial perfusion imaging: Defining a significant change and targeting management decisions. JACC Cardiovasc Imaging 2014;7:79-96.

    Article  Google Scholar 

  19. Koh AS, Gao F, Chin CT, Keng FY, Tan RS, Chua TS. Differential risk reclassification improvement by exercise testing and myocardial perfusion imaging in patients with suspected and known coronary artery disease. J Nucl Cardiol 2016;23:366-78.

    Article  Google Scholar 

  20. Yun HJ, Shah RV, Murthy VL. Exercise and Bayes’ Theorem: Some things never go out of style. J Nucl Cardiol 2016;23:379-83.

    Article  Google Scholar 

  21. Eshtehardi P, Isiadinso I, Shaw LJ. The benefits of advanced risk reclassification. J Nucl Cardiol 2016;23:384-6.

    Article  Google Scholar 

  22. Vitola JV, Wanderley MR Jr, Cerci RJ, Pereira Neto CC, Kormann O, Neto OF, et al. Outcome of patients with high-risk Duke treadmill score and normal myocardial perfusion imaging on spect. J Nucl Cardiol 2016;23:1291-300.

    Article  Google Scholar 

  23. Matsumoto N, Hirayama A. Clinical value of high duke treadmill score with myocardial perfusion SPECT. J Nucl Cardiol 2016;23:1301-3.

    Article  Google Scholar 

  24. Nakanishi R, Gransar H, Slomka P, Arsanjani R, Shalev A, Otaki Y, et al. Predictors of high-risk coronary artery disease in subjects with normal SPECT myocardial perfusion imaging. J Nucl Cardiol 2016;23:530-41.

    Article  Google Scholar 

  25. Yokota S, Mouden M, Ottervanger JP. High-risk coronary artery disease, but normal myocardial perfusion: A matter of concern? J Nucl Cardiol 2016;23:542-5.

    Article  Google Scholar 

  26. Bajaj NS, Singh S, Farag A, El-Hajj S, Heo J, Iskandrian AE, et al. The prognostic value of non-perfusion variables obtained during vasodilator stress myocardial perfusion imaging. J Nucl Cardiol 2016;23:390-413.

    Article  Google Scholar 

  27. Golzar Y, Olusanya A, Pe N, Dua SG, Golzar J, Gidea C, et al. The significance of automatically measured transient ischemic dilation in identifying severe and extensive coronary artery disease in regadenoson, single-isotope technetium-99m myocardial perfusion SPECT. J Nucl Cardiol 2015;22:526-34.

    Article  Google Scholar 

  28. Katz JS, Ruisi M, Giedd KN, Rachko M. Assessment of transient ischemic dilation (TID) ratio in gated SPECT myocardial perfusion imaging (MPI) using regadenoson, a new agent for pharmacologic stress testing. J Nucl Cardiol 2012;19:727-34.

    Article  CAS  Google Scholar 

  29. Hage FG, Ghimire G, Lester D, McKay J, Bleich S, El-Hajj S, et al. The prognostic value of regadenoson myocardial perfusion imaging. J Nucl Cardiol 2015;22:1214-21.

    Article  Google Scholar 

  30. Lester D, El-Hajj S, Farag AA, Bhambhvani P, Tauxe L, Heo J, et al. Prognostic value of transient ischemic dilation with regadenoson myocardial perfusion imaging. J Nucl Cardiol 2016;23:1147-55.

    Article  Google Scholar 

  31. Loffler AI, Bourque JM. Prognostic impact of TID in regadenoson MPI: Some patients and certain events. J Nucl Cardiol 2016;23:1156-9.

    Article  Google Scholar 

  32. Hage FG, Dean P, Iqbal F, Heo J, Iskandrian AE. A blunted heart rate response to regadenoson is an independent prognostic indicator in patients undergoing myocardial perfusion imaging. J Nucl Cardiol 2011;18:1086-94.

    Article  Google Scholar 

  33. Hage FG, Dean P, Bhatia V, Iqbal F, Heo J, Iskandrian AE. The prognostic value of the heart rate response to adenosine in relation to diabetes mellitus and chronic kidney disease. Am Heart J 2011;162:356-62.

    Article  CAS  Google Scholar 

  34. Mathur S, Shah AR, Ahlberg AW, Katten DM, Heller GV. Blunted heart rate response as a predictor of cardiac death in patients undergoing vasodilator stress technetium-99m sestamibi gated SPECT myocardial perfusion imaging. J Nucl Cardiol 2010;17:617-24.

    Article  Google Scholar 

  35. Bellam N, Veledar E, Dorbala S, Di Carli MF, Shah S, Eapen D, et al. Prognostic significance of impaired chronotropic response to pharmacologic stress Rb-82 PET. J Nucl Cardiol 2014;21:233-44.

    Article  Google Scholar 

  36. AlJaroudi W, Campagnoli T, Fughhi I, Wassouf M, Ali A, Doukky R. Prognostic value of heart rate response during regadenoson stress myocardial perfusion imaging in patients with end stage renal disease. J Nucl Cardiol 2016;23:560-9.

    Article  Google Scholar 

  37. Andrikopoulou E, Hage FG. Heart rate response to regadenoson: Making the case for its value in clinical practice. J Nucl Cardiol 2016;23:575-80.

    Article  Google Scholar 

  38. Brodov Y, Fish M, Rubeaux M, Otaki Y, Gransar H, Lemley M, et al. Quantitation of left ventricular ejection fraction reserve from early gated regadenoson stress Tc-99m high-efficiency SPECT. J Nucl Cardiol 2016;23:1251-61.

    Article  Google Scholar 

  39. Sharir T, Brodkin B, Kovalski G. Combined assessment of myocardial perfusion and left ventricular function by nuclear cardiology: The value of high-efficiency SPECT. J Nucl Cardiol 2016;23:1262-5.

    Article  Google Scholar 

  40. Elgendy IY, Mahmoud A, Shuster JJ, Doukky R, Winchester DE. Outcomes after inappropriate nuclear myocardial perfusion imaging: A meta-analysis. J Nucl Cardiol 2016;23:680-9.

    Article  Google Scholar 

  41. George BJ, Aban IB. An application of meta-analysis based on DerSimonian and Laird method. J Nucl Cardiol 2016;23:690-2.

    Article  Google Scholar 

  42. Beale C, Tilkemeier P. Understanding the past to appropriately guide us in the future. J Nucl Cardiol 2016;23:693-4.

    Article  Google Scholar 

  43. Doukky R, Hayes K, Frogge N. Appropriate use criteria for SPECT myocardial perfusion imaging: Are they appropriate for women? J Nucl Cardiol 2016;23:695-705.

    Article  Google Scholar 

  44. Druz RS. The feminine mystique of AUC. J Nucl Cardiol 2016;23:706-9.

    Article  Google Scholar 

  45. Sharir T, Pinskiy M, Pardes A, Rochman A, Prokhorov V, Kovalski G, et al. Comparison of the diagnostic accuracies of very low stress-dose with standard-dose myocardial perfusion imaging: Automated quantification of one-day, stress-first SPECT using a CZT camera. J Nucl Cardiol 2016;23:11-20.

    Article  Google Scholar 

  46. Duvall WL, Henzlova MJ. Nuclear cardiology as it should look in the twenty-first century. J Nucl Cardiol 2016;23:21-3.

    Article  Google Scholar 

  47. van Dijk JD, Jager PL, Ottervanger JP, de Boer J, Oostdijk AH, Engbers EM, et al. Development and validation of a patient-tailored dose regime in myocardial perfusion imaging using conventional SPECT. J Nucl Cardiol 2016;23:134-42.

    Article  Google Scholar 

  48. Thompson RC, Burgett EV. Patient centered imaging and the dose of radiopharmaceuticals. J Nucl Cardiol 2016;23:143-4.

    Article  Google Scholar 

  49. Abidov A, Hachamovitch R, Hayes SW, Ng CK, Cohen I, Friedman JD, et al. Prognostic impact of hemodynamic response to adenosine in patients older than age 55 years undergoing vasodilator stress myocardial perfusion study. Circulation 2003;107:2894-9.

    Article  Google Scholar 

  50. Bhatheja R, Francis GS, Pothier CE, Lauer MS. Heart rate response during dipyridamole stress as a predictor of mortality in patients with normal myocardial perfusion and normal electrocardiograms. Am J Cardiol 2005;95:1159-64.

    Article  Google Scholar 

  51. Venkataraman R, Hage FG, Dorfman TA, Heo J, Aqel RA, de Mattos AM, et al. Relation between heart rate response to adenosine and mortality in patients with end-stage renal disease. Am J Cardiol 2009;103:1159-64.

    Article  CAS  Google Scholar 

  52. Hage FG, Perry G, Heo J, Iskandrian AE. Blunting of the heart rate response to adenosine and regadenoson in relation to hyperglycemia and the metabolic syndrome. Am J Cardiol 2010;105:839-43.

    Article  CAS  Google Scholar 

  53. Iqbal FM, Al Jaroudi W, Sanam K, Sweeney A, Heo J, Iskandrian AE, et al. Reclassification of cardiovascular risk in patients with normal myocardial perfusion imaging using heart rate response to vasodilator stress. Am J Cardiol 2013;111:190-5.

    Article  Google Scholar 

Download references

Disclosure

Dr. Hage reports grant support from Astellas Pharma and Novartis Pharma.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fadi G. Hage MD, FASNC.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hage, F.G., AlJaroudi, W.A. Review of cardiovascular imaging in the journal of nuclear cardiology in 2016: Part 2 of 2—myocardial perfusion imaging. J. Nucl. Cardiol. 24, 1190–1199 (2017). https://doi.org/10.1007/s12350-017-0875-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12350-017-0875-2

Keywords

Navigation