Relationship between cord blood atherogenic index and birth weight in preeclampsia

  • Simmi Kharb
  • Smiti Nanda
  • Anudeep Batra
Original Article


The present study was designed to analyze cord blood atherogenic index (AI) in newborns of normal pregnant and preeclamptic subjects and to correlate them with birth weight and maternal AI. The study consisted of 50 healthy pregnant women (Group I: controls) and 50 women with preeclampsia. Ten milliliter cord blood was collected from placental end of umbilical cord and 5 ml of maternal venous sample was drawn from antecubital vein at the time of delivery. Serum was separated by centrifugation and Apo A-I and Apo B levels were analyzed by immunoturbidimetric Immunoassay kits. AI was calculated as ratio of Apo B to Apo A-I. Apo B levels were significantly elevated in Group II in both cord blood and maternal blood as compared to Group I (p < 0.001). Apo A-I levels were lower in maternal blood and higher in cord blood of group II. In maternal blood, AI was higher in Group II as compared to Group I (p < 0.001). In group I, a significant positive correlation was observed between cord blood AI and birth weight and values being higher in males. In group II, a significant negative correlation observed between cord blood AI and birth weight was higher in females.


Cord blood atherogenic index Birth weight Preeclampsia 


Conflict of interest



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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of BiochemistryPt. B.D. Sharma PGIMSRohtakIndia
  2. 2.Department of Obstetrics and GynecologyPt. B.D. Sharma PGIMSRohtakIndia
  3. 3.RohtakIndia

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