Mediterranean Journal of Nutrition and Metabolism

, Volume 3, Issue 2, pp 133–136 | Cite as

Reduced body cell mass in type 2 diabetes mellitus: reversal with a diabetes-specific nutritional formula

  • Patrizio Tatti
  • Patrizia di Mauro
  • Marisa Neri
  • Giuseppe Pipicelli
  • Felice Strollo
Original Article


Subjects with type 2 diabetes are in a continuous catabolic state due to increased neoglycogensis during most of the fasting and the postprandial period. We compared the body cell mass index (BCMI) of 257 subjects with type 2 diabetes mellitus (T2DM) and 216 non-diabetic controls and found a statistically significant lower value in the diabetic subjects. This abnormality was reversed after 6 months of treatment with a diabetes-specific nutritional formula. Furthermore, in a population of 715 diabetic subjects without other diseases, we found that the BCMI was inversely correlated with the prevailing HbA1c and the duration of the disease.


T2DM Nutrition Body cell mass 


Conflict of interest

Patrizio Tatti was an international speaker for the Abbott Co. No conflict of interest is reported for the remaining authors.


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Patrizio Tatti
    • 1
  • Patrizia di Mauro
    • 1
  • Marisa Neri
    • 1
  • Giuseppe Pipicelli
    • 2
  • Felice Strollo
    • 3
  1. 1.UOCA di Endocrinologia e DiabetologiaASL RMHRomeItaly
  2. 2.UOC Diabetologia e Dietologia, ASP CatanzaroCatanzaroItaly
  3. 3.UOC di Endocrinologia, INRCARomeItaly

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