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Gastric type III heterotopic pancreas presenting as adenomyoma in the antrum of the stomach: a case report

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Abstract

Although heterotopic pancreas usually occurs in the stomach and rarely presents as a submucosal tumor, an accurate preoperative diagnosis is often difficult because of the variety of clinical symptoms and findings depending on the size and location of the lesion. We experienced a case of gastric type III heterotopic pancreas presenting as a gastric adenomyoma in the antrum of the stomach. A 62-year-old woman visited a local hospital for epigastric discomfort. An esophagogastroduodenoscopy study indicated a submucosal tumor in the greater curvature of the gastric antrum. The patient underwent surgical resection of the tumor because it was enlarged. The histological sections of the resected specimen showed that the tumor was composed of ductular structures lined by tall columnar epithelia and a prominent smooth muscle stroma with no atypical cells. The tumor was compatible with Heinrich’s type III heterotopic pancreas, which presented as an adenomyoma of the stomach. These findings provide useful histological features and some insight into a better understanding of the embryonic origin and development of adenomyoma and heterotopic pancreas in the antrum of the stomach.

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Acknowledgements

The authors would like to thank Mrs. Jennifer Holmes for her excellent medical editing of the manuscript.

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Authors and Affiliations

  1. Department of Surgery, Chiba-Ken Saiseikai Narashino Hospital, Social Welfare Organization, Saiseikai Imperial Gift Foundation, 1-Chome 1-1 Izumi-cho, Narashino, Chiba, 275-8580, Japan

    Yoichi Sakurai, Kentaro Togasaki, Yusuke Nakamura, Hiroyuki Fukuda, Hirokazu Karaki & Tomohisa Okaya

  2. Department of Gastroenterology, Chiba-Ken Saiseikai Narashino Hospital, Social Welfare Organization, Saiseikai Imperial Gift Foundation, Chiba, Japan

    Futoshi Hirai & Michikazu Abe

  3. Pathology Division, Chiba-Ken Saiseikai Narashino Hospital, Social Welfare Organization, Saiseikai Imperial Gift Foundation, Chiba, Japan

    Isamu Sugano

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  1. Yoichi Sakurai
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  2. Kentaro Togasaki
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  3. Yusuke Nakamura
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  4. Hiroyuki Fukuda
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  5. Hirokazu Karaki
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  7. Futoshi Hirai
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  9. Isamu Sugano
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Correspondence to Yoichi Sakurai.

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Conflict of interest

Yoichi Sakurai, Kentaro Togasaki, Yusuke Nakamura, Hiroyuki Fukuda, Hirokazu Karaki, Tomohisa Okaya, Futoshi Hirai, Michikazu Abe, and Isamu Sugano declare that all authors have no conflicts of interest.

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All procedures followed were performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Sakurai, Y., Togasaki, K., Nakamura, Y. et al. Gastric type III heterotopic pancreas presenting as adenomyoma in the antrum of the stomach: a case report. Clin J Gastroenterol 17, 34–40 (2024). https://doi.org/10.1007/s12328-023-01872-0

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  • DOI: https://doi.org/10.1007/s12328-023-01872-0

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