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Unicentric Castleman’s disease of hepatic hilum and retroperitoneum: a case report for endoscopic ultrasonography differential diagnosis and a literature review

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Abstract

Castleman’s disease (CD) is a highly heterogeneous clinico-pathological entity belonging to the lymphoproliferative disorders. CD can occur in any part of the human body where lymph nodes are present. In addition, very few cases have been reported in hepatic hilum. Here, we present a case of a middle-aged female patient who was presented with abdominal pain and diagnosed as localized Castleman’s disease of hepatic hilar and retroperitoneal origin. Diagnosing CD is complex due to its resemblance to many other diseases. EUS and FNA may play a more important role in differential diagnosis of CD and other disease in digestive system.

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Acknowledgements

This work was supported by grants from National Natural Science Foundation of China (No. 81602432).

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Author notes

  1. Ting Yu and Sachin Mulmi Shrestha have contributed equally to this work.

Authors and Affiliations

  1. Department of Gastroenterology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China

    Ying Yin, Ting Yu & Sachin Mulmi Shrestha

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  1. Ying Yin
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  2. Ting Yu
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  3. Sachin Mulmi Shrestha
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Correspondence to Ting Yu or Sachin Mulmi Shrestha.

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There is no conflict of all the authors in financial interests or connections, direct or indirect, or other situations that might raise the question of bias in the work reported or the conclusions, implications, or opinions stated.

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The patient has provided informed consent for publication of the case, and the Ethics Review Board of Zhongda Hospital of Nanjing City approved the study.

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Yin, Y., Yu, T. & Mulmi Shrestha, S. Unicentric Castleman’s disease of hepatic hilum and retroperitoneum: a case report for endoscopic ultrasonography differential diagnosis and a literature review. Clin J Gastroenterol 14, 1250–1254 (2021). https://doi.org/10.1007/s12328-021-01418-2

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