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Long-term relapse-free treatment with endoscopic submucosal dissection combined with magnifying narrow-band imaging for a pregnant patient with flat-type condyloma acuminatum: a case report

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Abstract

Condyloma acuminatum, in the form of genital warts, usually results from an infection by human papillomavirus, one of the most common causes of sexually transmitted diseases. It develops after an incubation period of 3 weeks to 8 months after infection; flat lesions are significantly rare. Condyloma acuminatum is prevalent in the genitals, particularly in the anus of immunodeficient patients. This also occurs in women during menstrual period and pregnancy. Although a common treatment option for rectal and anal lesions, surgical resection is highly invasive and results in a high rate of recurrence. Recently, endoscopic submucosal dissection has been performed for anorectal lesions, but data on its long-term follow-up are not available. We report the case of an immunocompromised patient due to pregnancy who remained recurrence-free 27 months after en-bloc resection by endoscopic submucosal dissection, with adequate visualisation of the flat lesion’s safety margin, combined with magnifying narrow-band imaging.

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Abbreviations

CA:

Condyloma acuminatum

STDs:

Sexually transmitted diseases

ESD:

Endoscopic submucosal dissection

M-NBI:

Magnifying narrow-band imaging

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Authors and Affiliations

  1. Department of Gastroenterology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan

    Kenshi Matsumoto, Naoto Sakamoto, Takashi Murakami, Noboru Yatagai, Hirofumi Fukushima, Hiroya Ueyama, Tomoyoshi Shibuya & Akihito Nagahara

  2. Department of Human Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan

    Shou Tsuyama & Takashi Yao

Authors
  1. Kenshi Matsumoto
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  2. Naoto Sakamoto
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  3. Takashi Murakami
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  4. Noboru Yatagai
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  5. Shou Tsuyama
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  6. Hirofumi Fukushima
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  7. Hiroya Ueyama
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  8. Tomoyoshi Shibuya
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  9. Takashi Yao
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  10. Akihito Nagahara
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Corresponding author

Correspondence to Kenshi Matsumoto.

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Conflict of interest

Kenshi Matsumoto, Naoto Sakamoto, Takashi Murakami, Noboru Yatagai, Shou Tsuyama, Hirofumi Fukushima, Hiroya Ueyama, Tomoyoshi Shibuya, Takashi Yao and Akihito Nagahara declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Matsumoto, K., Sakamoto, N., Murakami, T. et al. Long-term relapse-free treatment with endoscopic submucosal dissection combined with magnifying narrow-band imaging for a pregnant patient with flat-type condyloma acuminatum: a case report. Clin J Gastroenterol 14, 439–445 (2021). https://doi.org/10.1007/s12328-020-01288-0

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  • DOI: https://doi.org/10.1007/s12328-020-01288-0

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