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Intestinal T-cell lymphoma presenting as colonic perforation in the setting of ulcerative colitis: a case report

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The intestinal T-cell lymphomas are a rare group of lymphatic malignancies arising from the gastrointestinal tract. They frequently manifest with non-specific clinical and radiographic findings that may mimic several other disease processes. The most common subtype is linked with refractory coeliac disease and commonly affects the small intestine. We report a case where the diagnosis was uncovered endoscopically in a patient presenting with colonic perforation on a background of long-standing ulcerative colitis. Surgical source control was required prior to considering chemotherapy, which is the usual treatment option in lymphatic malignancies. The case highlights the importance endoscopic evaluation in inflammatory conditions of the colon.

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We would like to thank Dr. Vanita Bhargava for her assistance with the histopathological component of this case report.

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Correspondence to Ali Phillip Mourad.

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Ali Mourad, Marie Shella De Robles and Robert Winn declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from the patient for publication of this case study during his time in our unit.

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Mourad, A.P., De Robles, M.S. & Winn, R.D. Intestinal T-cell lymphoma presenting as colonic perforation in the setting of ulcerative colitis: a case report. Clin J Gastroenterol 14, 176–180 (2021).

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