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Case report of lanthanum deposition in the esophagus

Clinical Journal of Gastroenterology volume 13, pages 683–687 (2020)Cite this article

Abstract

A 69-year-old woman had received hemodialysis for chronic renal failure and was taking lanthanum carbonate since 63 years of age. She presented with appetite loss and nausea. We performed esophagogastroduodenoscopy, which revealed multiple longitudinal white plaques in the esophagus. Lesion biopsies showed lanthanum deposition, and lanthanum carbonate was found histologically by energy-dispersive X-ray spectroscopy. The plaques of this patient appeared like those of dabigatran-induced esophagitis, and may have occurred due to long-term contact of the esophageal epithelium with lanthanum carbonate because patient spent time in lying state. Although a few studies regarding lanthanum deposition in the stomach have been conducted, there are no reports on lanthanum deposition in the esophagus. This case suggests that the presence of longitudinal white plaques in the esophagus may indicate lanthanum deposition.

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Acknowledgements

We thank Dr. Masaya Iwamuro (Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science) for his important contributions with SEM and EDS.

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Affiliations

  1. Department of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine, 5-Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan

    Tetsuya Tatsuta, Daisuke Chinda, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tosihiro Haga & Shinsaku Fukuda

  2. Division of Endoscopy, Hirosaki University Hospital, Aomori, Japan

    Tatsuya Mikami

  3. Aomori General Health Examination Center, Aomori, Japan

    Tadashi Shimoyama

  4. Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Aomori, Japan

    Tosihiro Haga & Hiroshi Kijima

Authors
  1. Tetsuya Tatsuta
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  2. Tatsuya Mikami
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  3. Daisuke Chinda
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  4. Kazuki Akitaya
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  5. Shohei Igarashi
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  6. Keisuke Hasui
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  7. Hidezumi Kikuchi
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  8. Hiroto Hiraga
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  9. Manabu Sawaya
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  10. Hirotake Sakuraba
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  11. Tadashi Shimoyama
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  12. Tosihiro Haga
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  13. Hiroshi Kijima
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  14. Shinsaku Fukuda
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Corresponding author

Correspondence to Daisuke Chinda.

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Conflict of interest

Tetsuya Tatsuta, Tatsuya Mikami, Daisuke Chinda, Kazuki Akitaya, Shohei Igarashi, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Manabu Sawaya, Hirotake Sakuraba, Tadashi Shimoyama, Tosihiro Haga, Hiroshi Kijima, and Shinsaku Fukuda declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Tatsuta, T., Mikami, T., Chinda, D. et al. Case report of lanthanum deposition in the esophagus. Clin J Gastroenterol 13, 683–687 (2020). https://doi.org/10.1007/s12328-019-01085-4

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  • DOI: https://doi.org/10.1007/s12328-019-01085-4

Keywords

  • Lanthanum carbonate
  • Multiple longitudinal white plaques
  • Energy-dispersive X-ray spectroscopy