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Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report

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Abstract

A 76-year-old man was diagnosed with multiple hepatocellular carcinomas (HCCs). He underwent right lobectomy and partial resection of the liver after transcatheter arterial embolization at our hospital. The pathology report was moderately differentiated HCC (fT4N0M0 Stage Iva, Vp1, Vv0). Follow-up CT revealed a lesion in the right ventricle 3 years after surgery. Moderately differentiated HCC was determined on myocardial biopsy, and the lesion was diagnosed as cardiac metastasis of HCC. No recurrence of HCC was observed in the liver. Radiation therapy (39 Gy/13 fr) was performed for the cardiac metastasis, and oral lenvatinib 8 mg/day was started. Evaluation by mRECIST on contrast-enhanced CT indicate a partial response (PR). Lenvatinib has been continued for 7 months. Cardiac metastasis of HCC is extremely rare; herein, we have also provided a literature reviews.

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Authors and Affiliations

  1. Department of Gastroenterology and Metabolism, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan

    Yosuke Tamura, Tomokazu Kawaoka, Hiroshi Aikata, Maiko Namba, Yasutomo Fujii, Kei Morio, Eisuke Murakami, Masami Yamauchi, Akira Hiramatsu, Takashi Nakahara & Michio Imamura

  2. Department of Cardiovascular Medicine, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan

    Tatsuya Maruhashi

  3. Department of Gastroenterological and Transplant Surgery, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan

    Tsuyoshi Kobayashi & Hideki Ohdan

  4. Department of Radiation Oncology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan

    Tomoki Kimura & Yasushi Nagata

  5. Department of Anatomical Pathology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan

    Kouji Arihiro

  6. Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8551, Japan

    Tomokazu Kawaoka

Authors
  1. Yosuke Tamura
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  2. Tomokazu Kawaoka
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  3. Hiroshi Aikata
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  4. Maiko Namba
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  5. Yasutomo Fujii
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  6. Kei Morio
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  7. Eisuke Murakami
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  8. Masami Yamauchi
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  9. Akira Hiramatsu
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  10. Takashi Nakahara
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  11. Michio Imamura
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  12. Tatsuya Maruhashi
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  13. Tsuyoshi Kobayashi
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  14. Hideki Ohdan
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  15. Tomoki Kimura
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  16. Yasushi Nagata
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  17. Kouji Arihiro
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  18. Kazuaki Chayama
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Correspondence to Tomokazu Kawaoka.

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Tamura, Y., Kawaoka, T., Aikata, H. et al. Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report. Clin J Gastroenterol 13, 421–427 (2020). https://doi.org/10.1007/s12328-019-01075-6

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  • DOI: https://doi.org/10.1007/s12328-019-01075-6

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