Pediatric short bowel syndrome (SBS) is a serious condition which occurs in children with congenital or acquired reduction in length of the small intestine. SBS results in excessive fluid loss, nutrient malabsorption, electrolyte abnormalities, increased susceptibility to infections, parenteral nutrition associated complications and affects weight gain and growth. In children, SBS is debilitating and uniformly fatal without treatment. The primary goal of treatment is to restore enteral autonomy and reduce long-term dependence on parenteral support by increasing the absorptive potential of the remnant intestine. In this review, the medical and surgical management of SBS including pharmacologic agents, parenteral nutrition, dietary strategies, surgical lengthening procedures, and small bowel transplant will be discussed.
Pediatric short bowel syndrome Intestinal rehabilitation Intestinal adaptation Surgical lengthening procedures Small bowel transplantation
Short bowel syndrome
Small intestinal bacterial overgrowth
Intensive care unit
Deep venous thrombosis
Intestinal failure-associated liver disease
Longitudinal intestinal lengthening and tailoring
Serial transverse enteroplasty
segmental reversal of the small bowel
Small bowel transplantation
Acute cellular rejection
Graft vs. host disease
Post-transplant lymphoproliferative disease
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All authors influenced the concept, wrote and revised the manuscript and approved of the final version.
The authors received no financial support for the research, authorship, and/or publication of this article.
Compliance with ethical standards
Conflict of interest
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.
Informed consent was obtained from all patients for being included in the study.
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