Clinical Journal of Gastroenterology

, Volume 11, Issue 2, pp 123–126 | Cite as

A case of superficial esophageal cancer invading into the submucosa following ductal involvement with microinvasion

  • Yugo Suzuki
  • Toshiro Iizuka
  • Naoko Inoshita
  • Daisuke Kikuchi
  • Shu Hoteya
  • Harushi Udagawa
Case Report


Microinvasion is considered one reason for diagnostic discrepancies among preoperative diagnostic modalities. Stromal invasion developing from ductal involvement is often observed in such cases. Herein, we present a case of superficial esophageal cancer with ductal involvement and microinvasion around it. The steep concavity with dot-like microvessels in the center of a protruded lesion was presented by endoscopic observation, which was lead to the diagnostic discrepancy between magnified endoscopy and endoscopic ultrasound. Histological findings showed the tumor invaded into a submucosal layer with ductal involvement and microinvasion around it, and confirmed that this endoscopic finding was caused be tumor ductal involvement. When encountering endoscopic findings similar to those shown in this case, preparation of serial sections, enabling the confirmation of ductal involvement and further invasion into the stroma, will lead to the accurate diagnosis.


Squamous cell carcinoma Ductal involvement Microinvasion 


Compliance with ethical standards

Conflict of interest

Yugo Suzuki, Toshiro Iizuka, Naoko Inoshita, Daisuke Kikuchi, Shu Hoteya and Harushi Udagawa declare that they have no conflict of interest.

Human Rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed Consent

Informed consent was obtained from all patients for being included in the study.


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Copyright information

© Japanese Society of Gastroenterology 2017

Authors and Affiliations

  • Yugo Suzuki
    • 1
  • Toshiro Iizuka
    • 1
  • Naoko Inoshita
    • 2
  • Daisuke Kikuchi
    • 1
  • Shu Hoteya
    • 1
  • Harushi Udagawa
    • 3
  1. 1.Department of GastroenterologyToranomon HospitalTokyoJapan
  2. 2.Department of PathologyToranomon HospitalTokyoJapan
  3. 3.Department of Gastrointestinal SurgeryToranomon HospitalTokyoJapan

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