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Multiple rectal carcinoid tumors in monozygotic twins

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Abstract

We report multiple rectal carcinoid tumors in monozygotic twins who, respectively, had 42 and 36 carcinoid tumors in the lower rectum. This is the first report about carcinoid tumors in monozygotic twins. Both twins developed a similar number of rectal carcinoids with a similar distribution. Investigation of their genetic background may provide information about the origin of these tumors.

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References

  1. Bosman FT, Carneiro F, Hruban RH, et al. WHO classification of tumors of the digestive system. Lyon: IARC; 2010.

    Google Scholar 

  2. Starker LF, Carling T. Molecular genetics of gastroenteropancreatic neuroendocrine tumors. Curr Opin Oncol. 2009;1:29–33.

    Article  Google Scholar 

  3. Takano J, Takano K. Pathogenesis and molecular genetics of carcinoid tumors/gastrointestinal neuroendocrine tumors. Nippon Rinsho. 2011;69:629–33.

    PubMed  Google Scholar 

  4. Tiziana D, Silvia P, Cinzia A, et al. Different patterns of 11q allelic losses in digestive endocrine tumors. Hum Pathol. 2002;33:322–9.

    Article  Google Scholar 

  5. Modlin IM, Oberg K, Chung DC, et al. Gastroenteropancreatic neuroendocrine tumours. Lancet Oncol. 2008;1:61–72.

    Article  Google Scholar 

  6. Sasou S, Suto S, Satoh T, et al. Multiple carcinoid tumors of the rectum: report of two cases suggesting the origin of carcinoid tumors. Pathol Int. 2012;62:699–703.

    Article  PubMed  Google Scholar 

  7. Soga J. Carcinoid of the rectum: tumors of the carcinoid family: Urgut endocrinomas. Acta Med Biol. 1982;29:157–201.

    Google Scholar 

  8. Neki K, Akiyoshi T, Konishi T, et al. Multiple rectal carcinoid tumors treated by laparoscopic intersphincteric resection: a case report. J Jpn Soc Endosc Surg. 2012;17:523–8.

    Google Scholar 

  9. Tanaka H, Okuda H, Yoshida Y, et al. Multiple rectal carcinoid tumors with 31 lesions, report of a case. Stomach Intest (Tokyo). 2003;38:1193–9.

    Google Scholar 

  10. Maroy B. Similar rectal carcinoid tumors of two siblings with curative endoscopic snare resection. J Clin Gastroenterol. 1997;24:124–5.

    Article  CAS  PubMed  Google Scholar 

  11. Hiripi E, Bermejo JL, Sundquist J, et al. Familial gastrointestinal carcinoid tumors and associated cancers. Ann Oncol. 2009;20:950–4.

    Article  CAS  PubMed  Google Scholar 

  12. Katdare MV, Fichera A, Heimann TM. Familial rectal carcinoid: report of two first-degree relatives with rectal carcinoid and review of the literature. Tech Coloproctol. 2006;10:143–6.

    Article  CAS  PubMed  Google Scholar 

  13. Hassan MM, Phan A, Li D, et al. Risk factors associated with neuroendocrine tumors: a US-based case-control study. Int J Cancer. 2008;123:867–73.

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Surgery, Yawata Chuo Hospital, Yawata, Japan

    Momoko Doi

  2. Department of Surgery, Kyoto Second Red Cross Hospital, Kyoto, Japan

    Momoko Doi, Osamu Ikawa & Hiroki Taniguchi

  3. Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan

    Takuji Kawamura

  4. Department of Histopathology and Cytology, Kyoto Second Red Cross Hospital, Kyoto, Japan

    Kanade Katsura

Authors
  1. Momoko Doi
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  2. Osamu Ikawa
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  3. Hiroki Taniguchi
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  4. Takuji Kawamura
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  5. Kanade Katsura
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Correspondence to Momoko Doi.

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Conflict of interest

Momoko Doi, Osamu Ikawa, Hiroki Taniguchi, Takuji Kawamura and Kanade Katsura declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Doi, M., Ikawa, O., Taniguchi, H. et al. Multiple rectal carcinoid tumors in monozygotic twins. Clin J Gastroenterol 9, 215–221 (2016). https://doi.org/10.1007/s12328-016-0662-7

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  • DOI: https://doi.org/10.1007/s12328-016-0662-7

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