Abstract
We report two cases of early gastric cancer (EGC) with spreading to heterotopic gastric glands (HGG). The first case was a submucosal-tumor-like EGC and proximal gastrectomy was performed. The second case was a slightly elevated EGC and endoscopic submucosal dissection was performed. In both cases, pathological results showed adenocarcinoma spreading to the HGG in the submucosa. The depth of cancer was diagnosed as intramucosal carcinoma because cancer was limited to the epithelium of HGG without invasion to the submucosal stroma. There is no clear guideline concerning the management of early gastric cancers with spreading to heterotopic gastric glands.
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Conflict of Interest: Tomoko Hagiwara, Naomi Kakushima, Kenichiro Imai, Masaki Tanaka, Toshitatsu Takao, Kinichi Hotta, Yuichiro Yamaguchi, Kohei Takizawa, Hiroyuki Matsubayashi, Hiroyuki Ono, Takuma Oishi, Takashi Nakajima declare that they have no conflict of interest.
Human/Animal Rights: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).
Informed Consent: Informed consent was obtained from all patients before treatment.
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Hagiwara, T., Kakushima, N., Imai, K. et al. Early gastric cancer with spreading to heterotopic gastric glands in the submucosa: a case report and review of the literature. Clin J Gastroenterol 7, 123–128 (2014). https://doi.org/10.1007/s12328-014-0455-9
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DOI: https://doi.org/10.1007/s12328-014-0455-9