Skip to main content

Advertisement

Log in

Clinical Analysis of 122 Cases with Mycoplasma Pneumonia Complicated with Atelectasis: A Retrospective Study

  • Original Research
  • Published:
Advances in Therapy Aims and scope Submit manuscript

Abstract

Introduction

This study aims to explore the clinical characteristics, treatment, and prognosis of mycoplasma pneumonia complicated with atelectasis.

Methods

A retrospective analysis was performed on 122 children with mycoplasma pneumonia complicated with atelectasis. These children were hospitalized in the Xiamen Campus of the Pediatric Hospital of Fudan University and the Children’s Hospital of Xiamen between December 2015 and December 2018. A diagnosis was made for each case on the basis of the clinical symptoms and signs, Mycoplasma pneumoniae-specific IgM antibody, and imaging results.

Results

Among the 122 cases with mycoplasma pneumonia complicated with atelectasis, all cases had retractable M. pneumoniae infection, 102 cases underwent fibrobronchoscopic lavage treatment, and all cases were treated with macrolide antibiotics after a definite diagnosis was made. Furthermore, 107 cases improved and were discharged. Follow-up was performed for 3–4 weeks for all patients, and all patients, including the five cases with retractable disease, recovered well.

Conclusion

The major clinical manifestations for M. pneumoniae pneumonia are fever and stimulatory dry cough. Macrolide antibiotics remain the treatment of choice.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Arnold FW, Summersgill JT, Lajoie AS, et al. A worldwide perspective of atypical pathogens in community-acquired pneumonia. Am J Respir Crit Care Med. 2007;175(10):1086–93. https://doi.org/10.1164/rccm.200603-350oc.

    Article  PubMed  Google Scholar 

  2. Hu YM, Jiang ZF, Shen KL, Shen Y. Chu Futang practical pediatrics. 8th ed. Beijing: Beijing People’s Medical Publishing Press; 2015. p. 1280–2 (In Chinese).

    Google Scholar 

  3. Haccuria A, Michils A, Michiels S, Van Muylem A. Exhaled nitric oxide: a biomarker integrating both lung function and airway inflammation changes. J Allergy Clin Immunol. 2014;134(3):554–9. https://doi.org/10.1016/j.jaci.2013.12.1070.

    Article  CAS  PubMed  Google Scholar 

  4. Yu H, Côté P, Shearer HM, et al. Effectiveness of passive physical modalities for shoulder pain: systematic review by the Ontario protocol for traffic injury management collaboration. Phys Ther. 2015;95(3):306–18. https://doi.org/10.2522/ptj.20140361.

    Article  PubMed  Google Scholar 

  5. Migneault A, Sauvageau S, Villeneuve L, et al. Chronically elevated endothelin levels reduce pulmonary vascular reactivity to nitric oxide. Am J Respir Crit Care Med. 2005;171(5):506–13. https://doi.org/10.1164/rccm.200403-340OC.

    Article  PubMed  Google Scholar 

  6. Marini S, Buonanno G, Stabile L, Ficco G. Short-term effects of electronic and tobacco cigarettes on exhaled nitric oxide. Toxicol Appl Pharmacol. 2014;278(1):9–15. https://doi.org/10.1016/j.taap.2014.04.004.

    Article  CAS  PubMed  Google Scholar 

  7. Chiang WC, Teoh OH, Chong CY, Goh A, Tang JP, Chay OM. Epidemiology, clinical characteristics and antimicrobial resistance patters of community-acquired pneumonia in 1702 hospitalized children in Singapore. Respirology. 2007;12(2):254–61. https://doi.org/10.1111/j.1440-1843.2006.01036.x.

    Article  PubMed  Google Scholar 

  8. Shimoda T, Obase Y, Kishikawa R, Iwanaga T. Influence of cigarette smoking on airway inflammation and inhaled corticosteroid treatment in patients with asthma. Allergy Asthma Proc. 2016;37(4):50–8. https://doi.org/10.2500/aap.2016.37.3944.

    Article  PubMed  Google Scholar 

  9. Vardavas CI, Anagnostopoulos N, Kougias M, Evangelopoulou V, Connolly GN, Behrakis PK. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest. 2012;141(6):1400–6. https://doi.org/10.1378/chest.11-2443.

    Article  CAS  PubMed  Google Scholar 

  10. Jiang W, Yan Y, Ji W, Wang Y, Chen Z. Clinical significance of different bacterial load of Mycoplasma pneumoniae in patients with Mycoplasma pneumoniae pneumonia. Braz J Infect Dis. 2014;18(2):124–8. https://doi.org/10.1016/j.bjid.2013.06.004.

    Article  PubMed  Google Scholar 

  11. Grabowska-Krawiec P. Contemporary risks of infections by Mycoplasma pneumoniae and Chlamydophila pneumoniae. Pol Merkur Lekarski. 2012;33(197):270–3.

    PubMed  Google Scholar 

  12. Matsuda Y, Chigusa Y, Kondoh E, Ito I, Ueda Y, Mandai M. A case of macrolide-refractory Mycoplasma pneumoniae pneumonia in pregnancy treated with garenoxacin. Case Rep Obstet Gynecol. 2017;2017:3520192. https://doi.org/10.1155/2017/3520192.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Rey JW, Deris N, Marquardt JU, et al. High-definition endoscopy with iScan and Lugol’s solution for the detection of inflammation in patients with nonerosive reflux disease: histologic evaluation in comparison with a control group. Dis Esophagus. 2016;29(2):185–91. https://doi.org/10.1111/dote.12308.

    Article  CAS  PubMed  Google Scholar 

  14. Hulman S, Kushner H, Katz S, Falkner B. Can cardiovascular risk be predicted by newborn, childhood, and adolescent body size? An examination of longitudinal data in urban African Americans. J Pediatr. 1998;132:90–7. https://doi.org/10.1016/s0022-3476(98)70491-3.

    Article  CAS  PubMed  Google Scholar 

  15. Biondi E, McCulloh R, Alverson B, Klein A, Dixon A, Ralston S. Treatment of mycoplasma pneumonia: a systematic review. Pediatrics. 2014;133(6):1081–90. https://doi.org/10.1542/peds.2013-3729.

    Article  PubMed  Google Scholar 

  16. Bébéar C, Pereyre S, Peuchant O. Mycoplasma pneumoniae: susceptibility and resistance to antibiotics. Future Microbiol. 2011;6(4):423–31. https://doi.org/10.2217/fmb.11.18.

    Article  CAS  PubMed  Google Scholar 

  17. Ma EL, Wang C, Wang MW. Advances in research on immune-regulatory effects of macrolide antibiotics. World Notes Antibiot. 2003;1:1–4 (In Chinese).

    Google Scholar 

  18. Xin DL, Shi DW. Advances in antibiotics treatment of macrolide antibiotics-resistant Mycoplasma pneumoniae pneumonia. Chin J Pract Pediatr Clin. 2013;22:1695–7. https://doi.org/10.3760/cma.j.issn.2095-428x.2013.22.005(In Chinese).

    Article  Google Scholar 

  19. Meyer Sauteur PM, Vall Rossurn AM, Vink C. Mycoplasma pneumoniae in children: carriage, pathogenesis, and antibiotic resistance. Curr Opin Infect Dis. 2014;27(3):220–7. https://doi.org/10.1097/QCO.0000000000000063.

    Article  CAS  PubMed  Google Scholar 

  20. Jin J, Wang LB, Zhang MZ, Zhou BH, Zhi DJ. Clinical features and bronchoscopy treatment for 378 patients of Mycoplasma pneumoniae pneumonia in children. Chongqing Med. 2015;44(34):4815–7. https://doi.org/10.3969/j.issn.1671-8348.2015.34.022(In Chinese).

    Article  Google Scholar 

  21. Zhuo Z, Li F, Chen X, Jin P, Guo Q, Wang H. Mycoplasma pneumonia combined with pulmonary infarction in a child. Int J Clin Exp Med. 2015;8(1):1482–6.

    PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

We thank the participants of the study.

Funding

No funding or sponsorship was received for this study or publication of this article. The Rapid Service Fees were funded by the authors.

Authorship

All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published.

Disclosures

De-Quan Su, Zhi-Qiang Zhuo, and Jin-Fan Li declare that they have no conflict of interest.

Compliance with Ethics Guidelines

This study was conducted in accordance with the 1964 declaration of Helsinki and its later amendments and was approved by the Ethics Committee of the Children’s Hospital of Fudan University Xiamen Branch. Written informed consent was obtained from all participants.

Data Availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhi-Qiang Zhuo.

Additional information

Enhanced Digital Features

To view enhanced digital features for this article go to https://doi.org/10.6084/m9.figshare.9980762.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Su, DQ., Li, JF. & Zhuo, ZQ. Clinical Analysis of 122 Cases with Mycoplasma Pneumonia Complicated with Atelectasis: A Retrospective Study. Adv Ther 37, 265–271 (2020). https://doi.org/10.1007/s12325-019-01129-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12325-019-01129-8

Keywords

Navigation