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Table 2 Baseline demographic characteristics of the Chinese populations included in the vortioxetine studies

From: Pharmacokinetics and Safety of Vortioxetine in the Chinese Population

Subject/patient characteristics Study 1 Study 2 Study 3 [21]
Single dose (overall) Single-dose group (overall) Multiple-dose group (overall) Vortioxetine group
Men, n (%) 8 (50) 16 (50) 16 (50) 60 (48.4)
Women, n (%) 8 (50) 16 (50) 16 (50) 64 (51.6)
Healthy subjects, n 16 64 NA
Patients with MDD, n NA NA NA 124
Age, mean ± SD (range), years 22 ± 2.3 (18–28) 24 ± 2.1 (20–29) 23 ± 2.5 (18–33) 36.3 ± 11.1 (19–63)
Height, mean ± SD (range), cm 169 ± 6.3 (158–178) 166 ± 8.0 (150–180) 166 ± 7.0 (157–179) 165.2 ± 8.3 (150–190)
Weight, mean ± SD (range), kg 62 ± 5.9 (54–73) 57.7 ± 8.03 (45–74) 60.3 ± 7.24 (50–75) 62.2 ± 12.8 (37.2–99)
BMI, mean ± SD (range), kg/m2 22 ± 1.6 (19–24) 20.9 ± 1.55 (18.7–23.4) 21.8 ± 1.62 (18.5–23.7) 22.7 ± 3.6 (15.7–32.1)
  1. BMI body mass index, MDD major depressive disorder, NA not applicable, SD standard deviation