Abstract
We present the case of a 35-year-old patient suffering from an untreated solitary osteochondroma and subsequent rare transformation to a dedifferentiated chondrosarcoma. This case highlights the potential risk of malignant transformation and raises the question of patient and clinician responsibility in identifying changes in a premalignant condition.
References
Fletcher CDM, Unni KK, Mertens F (2002) World Health Organisation classification of tumors: pathology and genetics of tumors in soft tissue and bone. I. Press, Lyon, pp 234–236
Florez B et al (2008) Solitary osteochondroma long-term follow-up. J Pediatr Orthop Part B 2:91–94
Schajowicz F (1994) Tumors and tumor-like lesions of bone. Springer, Berlin
Murphey M, Choi J, Kransdorf M (2000) Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics 5:1407–1434
Campanacci M (1999) Bone and soft tissue tumors. Springer/Philadelphia-Lippincott, Padoa/Philadelphia, pp 179–196
Stieber JR, Dormans JP (2005) Manifestations of hereditary multiple exostoses. J Am Acad Orthop Surg 2:110–120
Mirra J (1989) Bone tumors: diagnosis and treatment. J.B. Lippincott, Philadelphia
Resnick D, Kyriakos M, Greenway GD (1995) Osteochondroma. In: Resnick D (ed) Diagnosis of bone and joint disorders. Saunders, Philadelphia, pp 3725–3746
Giudici MA, Moser RP, Kransdorf MJ (1993) Cartilagenous bone tumours. Radiol Clin North Am 49:1890–1897
Scarborough MT, Moreau G (1996) Benign cartilage tumors. Orthop Clin North Am 27:583–589
Ahmed AR et al (2003) Secondary chondrosarcoma in osteochondroma: report of 107 patients. Clin Orthop Relat Res 411:193–206
Malghem J et al (1992) Benign Osteochondromas and exostotic chondrosarcomas: evaluation of cartilage cap thickness by ultrasound. Skeletal Radiol 21:33–37
Grimer RJ et al (2007) Dedifferentiated chondrosarcoma: prognostic factors and outcome from a European group. Eur J Cancer 14:2060–2065
Wuisman P, Jutte P, Ozaki T (1997) Secondary chondrosarcoma in osteochondromas: medullary extension in 15 of 45 cases. Acta Orthop Scand 68:394–400
Miller SL, Hoffer FA (2001) Malignant and benign bone tumors. Radiol Clin North Am 39:673–699
Altay M et al (2007) Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients. J Orthop Sci 5:415–423
Koplas M, Winalski C, Sundaram M (2007) What’s your diagnosis? Osteochondroma with large bursa clinically mimicking malignant transformation. Orthopedics 7(505):581–583
Garrison RC et al (1982) Chondrosarcoma arising in osteochondroma. Cancer 9:1890–1897
Chin KR, Kharrazi FD, Miller B (2000) Osteochondromas of the distal aspect of the tibia and fibula: natural history and treatment. J Bone Jt Surg Am 82:1269–2000
Davids JR, Glancy GL, Eilert RE (1991) Fracture through the stalk of pedunculated osteochondromas. Clin Orthop 271:258
Galasso O, Mariconda M, Milano C (2009) An enlarging distal tibia osteochondroma in the adult patient. J Am Podiatric Med Assoc 2:157–161
Lee FY et al (1999) Chondrosarcoma of bone: an assessment of outcome. J Bone Jt Surg Am 3:326–338
Staals EL et al (2007) Dedifferentiated chondrosarcomas arising in preexisting osteochondromas. J Bone Jt Surg Am Vol 5:987–993
Acknowledgments
None to declare.
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Additional information
Andrew P Dekker and Robert J Grimer authors contributed equally to this work.
Rights and permissions
About this article
Cite this article
Dekker, A.P., Grimer, R.J. Transformation of solitary osteochondroma to dedifferentiated chondrosarcoma arising in the distal radius: a case report. Musculoskelet Surg 97, 89–92 (2013). https://doi.org/10.1007/s12306-012-0226-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12306-012-0226-z