Skip to main content

Fine tuning of auxin signaling by miRNAs

Physiology and Molecular Biology of Plants volume 14, pages 81–90 (2008)Cite this article

Abstract

microRNAs (miRNAs) constitute a major class of endogenous non-coding regulatory small RNAs. They are present in a variety of organisms from algae to plants and play an important role in gene regulation. The miRNAs are involved in various biological processes, including differentiation, organ development, phase change, signaling, disease resistance and response to environmental stresses. This review provides a general background on the discovery, history, biogenesis and function of miRNAs. However, the focus is on the role for miRNA in controlling auxin signaling to regulate plant growth and development.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  • Able, S. (2007). Auxin is surfacing. ACS Chem Biol., 2: 380–384.

    Google Scholar 

  • Achard, P., Herr, A., Baulcombe, D.C. and Harberd, N.P. (2004). Modulation of floral development by a gibberellin-regulated microRNA. Development, 131: 3357–3365.

    PubMed  CAS  Google Scholar 

  • Aida, M., Ishida, T., Fukaki, H., Fujisawa, H. and Tasaka, M. (1997). Genes involved in organ separation in Arabidopsis: an analysis of the cup shaped cotyledon mutant. Plant Cell, 9: 841–857.

    PubMed  CAS  Google Scholar 

  • Adai, A., Johnson, C., Mlotshwa, S., Archer-Evans, S., Manocha, V., Vance, V. and Sundaresan, V. (2005). Computational prediction of miRNAs in Arabidopsis thaliana. Genome Res., 15: 78–91.

    PubMed  CAS  Google Scholar 

  • Allen, E., Xie, Z., Gustafson, A.M., Sung, G.H., Spatafora, J.W. and Carrington, J.C. (2004). Evolution of microRNA genes by inverted duplication of target gene sequences in Arabidopsis thaliana. Nat Genet., 36: 1282–1290.

    PubMed  CAS  Google Scholar 

  • Allen, E., Xie, Z., Gustafson, A.M. and Carrington, J.C. (2005). microRNA-directed phasing during trans-acting siRNA biogenesis in plants. Cell, 121: 207–221.

    PubMed  CAS  Google Scholar 

  • Alvarez, J.P., Pekker, I., Goldshmidt, A., Blum, E., Amsellem, Z. and Eshed, Y. (2006). Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species. Plant Cell, 18: 1134–1151.

    PubMed  CAS  Google Scholar 

  • Aukerman, M.J. and Sakai, H. (2003). Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes. Plant Cell, 15: 2730–2741.

    PubMed  CAS  Google Scholar 

  • Axtell, M.J. and Bartel, D.P. (2005). Antiquity of microRNAs and their targets in land plants. Plant Cell, 17: 1658–1673.

    PubMed  CAS  Google Scholar 

  • Bao, N., Lye, K.W. and Barton, M.K. (2004). MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNAs are required for methylation of the template chromosome. Dev Cell., 7: 653–662.

    PubMed  CAS  Google Scholar 

  • Bartel, B. and Bartel, D.P. (2003). MicroRNAs: at the root of plant development? Plant Physiol., 132: 709–717.

    PubMed  CAS  Google Scholar 

  • Bartel, D.P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116: 281–297.

    PubMed  CAS  Google Scholar 

  • Bollman, K.M., Aukerman, M.J., Park, M.Y., Hunter, C., Berardini, T.Z. and Poethig, R.S. (2003). HASTY, the Arabidopsis ortholog of exportin 5/MSN5, regulates phase change and morphogenesis. Development, 130: 1493–1504.

    PubMed  CAS  Google Scholar 

  • Boutet, S., Vazquez, F., Liu, J., Beclin, C., Fagard, M., Gratias, A., Morel, J.B., Crete, P., Chen, X. and Vaucheret, H. (2003). Arabidopsis HEN1: a genetic link between endogenous miRNA controlling development and siRNA controlling transgene silencing and virus resistance. Curr Biol., 13: 843–848.

    PubMed  CAS  Google Scholar 

  • Bowman, J.L. (2004). Class III HD-Zip gene regulation, the golden fleece of ARGONAUTE activity? Bioessays, 26: 938–942.

    PubMed  CAS  Google Scholar 

  • Cai, X., Hagedorn, C.H. and Cullen, B.R. (2004). Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA, 10: 1957–1966.

    PubMed  CAS  Google Scholar 

  • Carrington, J.C. and Ambros, V. (2003). Role of microRNAs in plant and animal development. Science, 301: 336–338.

    PubMed  CAS  Google Scholar 

  • Chapman, E.J., Prokhnevsky, A.I, Gopinath, K., Dolja, V.V. and Carrington, J.C. (2004). Viral RNA silencing suppressors inhibit the microRNA pathway at an intermediate step. Genes Dev., 18: 1179–1186.

    PubMed  CAS  Google Scholar 

  • Chen, C.Z., Li, L., Lodish, H.F. and Bartel, D.P. (2004). MicroRNAs modulate hematopoietic lineage differentiation. Science, 303: 83–86.

    PubMed  CAS  Google Scholar 

  • Chen, X. (2004). A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. Science, 303: 2022–2025.

    PubMed  CAS  Google Scholar 

  • Denli, A.M., Tops, B.B.J., Plasterk, R.H.A. and Ketting, R.F. (2004). Processing of primary microRNAs by the microprocessor complex. Nature, 432: 231–235.

    PubMed  CAS  Google Scholar 

  • Dezulian, T., Remmert, M., Palatnik, J.F., Weigel, D. and Huson, D.H. (2006). Identification of plant microRNA homologs. Bioinformatics, 22: 359–360.

    PubMed  CAS  Google Scholar 

  • Dharmasiri, N., Dharmasiri, S., Weijers, D., Lechner, E., Yamada, M., Hobbie, L., Ehrismann, J.S., Jurgens, G. and Estelle, M. (2005). Plant development is regulated by a family of auxin receptor F box proteins. Dev Cell., 9: 109–119.

    PubMed  CAS  Google Scholar 

  • Emery, J.F., Floyd, S.K., Alvarez, J., Eshed, Y., Hawker, N.P., Izhaki, A., Baum, S.F. and Bowman, J.L. (2003). Radial patterning of Arabidopsis shoots by class III HD-ZIP and KANADI genes. Curr. Biol., 13: 1768–1774.

    PubMed  CAS  Google Scholar 

  • Fleming, A.J. (2006). Plant signalling: the inexorable rise of auxin. Trends Cell Biol., 16: 397–402.

    PubMed  CAS  Google Scholar 

  • Gray, W.M., Kepinski, S., Rouse, D., Leyser, O., and Estelle, M. (2001). Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins. Nature, 414: 271–276.

    PubMed  CAS  Google Scholar 

  • Griffiths-Jones, S., Grocock, R.J., Dongen, S.V., Bateman, A. and Enright, A.J. (2006). miRBase: micro sequence, targets and gene nomenclature. Nuc. Acids Res., 34: 140–144.

    Google Scholar 

  • Guilfoyle, T.J., and Hagen, G. (2001). Auxin response factors. J. Plant Growth Regul., 10: 281–291.

    Google Scholar 

  • Guo, H.S., Xie, Q., Fei, J.F. and Chua, N.H. (2005). MicroRNA directs mRNA cleavage of the transcription factor NAC1 to downregulate auxin signals for Arabidopsis lateral root development. Plant Cell, 17: 1376–1386.

    PubMed  CAS  Google Scholar 

  • Hagen, G. and Guilfoyle, T. (2002). Auxin-responsive gene expression: genes, promoters and regulatory factors. Plant Mol. Biol., 49: 373–385.

    PubMed  CAS  Google Scholar 

  • Hammond, S.M. (2005). Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett., 579: 5822–5829.

    PubMed  CAS  Google Scholar 

  • Han, M.H., Goud, S., Song, L. and Fedoroff, N. (2004). The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation. Proc. Natl. Acad. Sci. USA., 101: 1093–1098.

    PubMed  CAS  Google Scholar 

  • Hartig, K. and Beck, E. (2006). Crosstalk between auxin, cytokinins, and sugars in the plant cell cycle. Plant Biol. (Stuttg)., 8: 389–396.

    CAS  Google Scholar 

  • Hibara, K., Takada, S. and Tasaka, M. (2003). CUC1 gene activates the expression of SAM-related genes to induce adventitious shoot formation. Plant J., 36: 687–696.

    PubMed  CAS  Google Scholar 

  • Hibara, K., Karim, M.R., Takada, S., Taoka, K., Furutani, M., Aida, M. and Tasaka, M. (2006). Arabidopsis CUPSHAPED COTYLEDON3 regulates postembryonic shoot meristem and organ boundary formation. Plant Cell, 18: 2946–2957.

    PubMed  CAS  Google Scholar 

  • Jones-Rhoades, M.W. and Bartel, D.P. (2004). Computational identification of plant microRNAs and their targets, including a stress-induced miRNA. Mol. Cell, 14: 787–799.

    PubMed  CAS  Google Scholar 

  • Juarez, M.T., Kui, J.S., Thomas, J., Heller, B.A. and Timmermans, M.C. (2004). microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity. Nature, 428: 84–88.

    PubMed  CAS  Google Scholar 

  • Kasschau, K.D., Xie, Z., Allen, E., Llave, C., Chapman, E.J., Krizan, K.A. and Carrington, J.C. (2003). P1-HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function extent of virus invasion. RNA silencing involves recognition and processing of double-stranded RNA. Dev Cell, 4: 205–217.

    PubMed  CAS  Google Scholar 

  • Kidner, C.A. and Martienssen, R.A. (2005). The role of ARGONAUTE1 (AGO1) in meristem formation and identity. Dev Biol., 280: 504–517.

    PubMed  CAS  Google Scholar 

  • Kim, J., Jung, J.H., Reyes, J.L., Kim, Y.S., Kim, S.Y., Chung, K.S., Kim, J.A., Lee, M., Lee, Y., Kim, V., Chua, N.H. and Park, C.M. (2005). MicroRNA-directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems. Plant J., 42: 84–94.

    PubMed  CAS  Google Scholar 

  • Ko, J.H., Prassinos, C. and Han, K.H. (2006). Developmental and seasonal expression of PtaHB1, a Populus gene encoding a class III HD-Zip protein, is closely associated with secondary growth and inversely correlated with the level of microRNA (miR166). New Phytologist, 169: 469–478.

    PubMed  CAS  Google Scholar 

  • Kurihara, Y. and Watanabe, Y. (2004). Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions. Proc Natl Acad Sci. USA., 101: 12753–12758.

    PubMed  CAS  Google Scholar 

  • Kurihara, Y., Takashi, Y. and Watanabe, Y. (2006). The interaction between DCL1 and HYL1 is important for efficient and precise processing of pri-miRNA in plant microRNA biogenesis. RNA, 12: 206–212.

    PubMed  CAS  Google Scholar 

  • Lai, E.C, Tomancak, P., Williams, R.W. and Rubin, G.M. (2003). Computational identification of Drosophila microRNA genes. Genome Biol., 4: 169–172.

    Google Scholar 

  • Laufs, P., Peaucelle, A., Morin, H. and Traas, J. (2004). MicroRNA regulation of the CUC genes is required for boundary size control in Arabidopsis meristems. Development, 131: 4311–4322.

    PubMed  CAS  Google Scholar 

  • Lauter, N., Kampani, A., Carlson, S., Goebel, M. and Moose, S.P. (2005). microRNA172 down-regulates glossy15 to promote vegetative phase change in maize. Proc. Natl. Acad. Sci. USA., 102: 9412–9417.

    PubMed  CAS  Google Scholar 

  • Lee, R.C., Feinbaum, R.L. and Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75: 843–854.

    PubMed  CAS  Google Scholar 

  • Lee, Y., Kim, M., Han, J., Yeom, K.H., Lee, S., Baek, S.H. and Kim, V.N. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 23:4051–4060.

    PubMed  CAS  Google Scholar 

  • Lewis, B.P., Burge, C.B. and Bartel, D.P. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 120: 15–20.

    PubMed  CAS  Google Scholar 

  • Lim, L., Lau, N., Weinstein, E., Abdelhakim, A., Yekta, S., Rhoades M., Burge, C. and Bartel, D. (2003). The microRNAs of Caenorhabditis elegans. Genes Dev., 17: 991–1008.

    PubMed  CAS  Google Scholar 

  • Lindow, M., Jacobsen, A., Nygaard, S., Mang, Y. and Krogh, A. (2007) Intragenomic Matching Reveals a Huge Potential for miRNA-Mediated Regulation in Plants. PLoS Comput. Biol., 3: e238.

    PubMed  Google Scholar 

  • Liu, B., Li, P., Li, X., Liu, C., Cao, S., Chu, C., and Cao, X. (2005). Loss of Function of OsDCL1 affects microRNA accumulation and causes developmental defects in rice. Plant Physiol., 139: 296–305.

    PubMed  CAS  Google Scholar 

  • Liu, P.P., Montgomery, T.A., Fahlgren, N., Kasschau, K.D., Nonogaki, H. and Carrington, J.C. (2007) Repression of AUXIN RESPONSE FACTOR 10 by microRNA160 is critical for seed germination and post-germination stages. Plant J., 52: 133–146.

    PubMed  CAS  Google Scholar 

  • Llave, C., Xie, Z., Kasschau, K.D. and Carrington, J.C. (2002). Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science, 297: 2053–2056.

    PubMed  CAS  Google Scholar 

  • Lohmann, J.U., and Weigel, D. (2002). Building beauty: The genetic control of floral patterning. Dev. Cell., 2: 135–142.

    PubMed  CAS  Google Scholar 

  • Lu, S., Sun, Y.H., Shi, R., Clark, C., Li, L. and Chiang, V.L. (2005). Novel and mechanical stress-responsive MicroRNAs in Populus trichocarpa that are absent from Arabidopsis. Plant Cell, 17: 2186–2203.

    PubMed  CAS  Google Scholar 

  • Mallory, A.C., Reinhart, B.J., Jones-Rhoades, M.W., Tang, G., Zamore, P.D., Barton, M.K. and Bartel, D.P. (2004a). MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5′ region. EMBO J., 23: 3356–3364.

    PubMed  CAS  Google Scholar 

  • Mallory, A.C., Dugas, D.V., Bartel, D.P. and Bartel, B. (2004b). MicroRNA regulation of NAC-domain targets is required for proper formation and separation of adjacent embryonic, vegetative, and floral organs. Curr Biol., 14: 1035–1046.

    PubMed  CAS  Google Scholar 

  • Mallory, A.C., Bartel, D.P. and Bartel, B. (2005). MicroRNA-Directed Regulation of Arabidopsis AUXIN RESPONSE FACTOR17 Is Essential for Proper Development and Modulates Expression of Early Auxin Response Genes. The Plant Cell, 17:1360–1375.

    PubMed  CAS  Google Scholar 

  • McHale, N.A. and Koning, R.E. (2004). MicroRNA-directed cleavage of Nicotiana sylvestris PHAVOLUTA mRNA regulates the vascular cambium and structure of apical meristems. Plant Cell, 16:1730–1740.

    PubMed  CAS  Google Scholar 

  • Millner, P.A. (1995). The auxin signal. Curr. Opin. Cell. Biol., 7: 224–231.

    PubMed  CAS  Google Scholar 

  • Molnár, A., Schwach, F., Studholme, D.J., Thuenemann, E.C. and Baulcombe, D.C. (2007). miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii. Nature, 447: 1126–1129.

    PubMed  Google Scholar 

  • Nam, J.W., Kim, J., Kim, S.K. and Zhang, B.T. (2005). ProMiR II: a web server for the probabilistic prediction of clustered, nonclustered, conserved and nonconserved microRNAs. Nucleic Acids Res., (Web Server issue) 34: W455–W458.

    Google Scholar 

  • Navarro, L., Dunoyer, P., Jay, F., Arnold B., Dharmasiri, N., Estelle, M. Voinnet, O. and Jones, J.D.G. (2006). A plant miRNA contribute to antibacterial resistance by repressing auxin Signaling. Science, 312: 436–439.

    PubMed  CAS  Google Scholar 

  • Ori, N., Cohen, A.R., Etzioni, A., Brand, A., Yanai, O., Shleizer, S., Menda, N., Amsellem, Z., Efroni, I., Pekker, I., Alvarez, J.P., Blum, E., Zamir, D. and Eshed, Y. (2007). Regulation of LANCEOLATE by miR319 is required for compound-leaf development in tomato. Nat Genet., 39: 787–791.

    PubMed  CAS  Google Scholar 

  • Palatnik, J.F., Allen, E., Wu X, Schommer, C., Schwab, R., Carrington, J.C. and Weigel, D. (2003) Control of leaf morphogenesis by microRNAs. Nature, 425: 257–263.

    PubMed  CAS  Google Scholar 

  • Papp, I., Mette, M.F., Aufsatz, W., Daxinger, L., Schauer, S.E., Ray, A., van der Winden, J., Matzke, M. and Matzke, A.J. (2003). Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors. Plant Physiol., 132: 1382–1390.

    PubMed  CAS  Google Scholar 

  • Park, W., Li J., Song, R., Messing, J. and Chen, X. (2002). CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr Biol., 12: 1484–1495.

    PubMed  CAS  Google Scholar 

  • Park, M.Y., Wu G, Gonzalez-Sulser, A., Vaucheret, H. and Poethig R.S. (2005). Nuclear processing and export of microRNAs in Arabidopsis. Proc. Natl. Acad. Sci. USA, 102: 3691–3696.

    PubMed  CAS  Google Scholar 

  • Pasquinelli, A.E., Reinhart, B.J., Slack, F., Martindale, M.Q., Kuroda, M.I., Maller, B., Hayward, D.C., Ball, E.E., Degnan, B., Muller, P., Spring, J., Srinivasan, A., Fishman, M., Finnerty, J., Corbo, J., Levine, M., Leahy, P., Davidson, E. and Ruvkun, G. (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 408: 86–89.

    PubMed  CAS  Google Scholar 

  • Quint, M. and Gray, W.M. (2006). Auxin signaling. Curr Opin Plant Biol., 9: 448–453.

    PubMed  CAS  Google Scholar 

  • Reinhart, B.J., Slack, F.J., Basson, M., Pasquinelli, A.E., Bettinger, J.C., Rougvie, A.E., Horvitz, H.R. and Ruvkun, G. (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 403: 901–906.

    PubMed  CAS  Google Scholar 

  • Reinhart, B.J., Weinstein, E.G., Rhoades, M.W., Bartel, B. and Bartel, D.P. (2002). MicroRNAs in plants. Genes Dev., 16: 1616–1626.

    PubMed  CAS  Google Scholar 

  • Rhoades, M.W., Reinhart, B.J., Lim, L.P., Burge, C.B., Bartel, B. and Bartel, D.P. (2002). Prediction of plant microRNA targets. Cell, 110: 513–520.

    PubMed  CAS  Google Scholar 

  • Rhoades, M.W., Reinhart, B.J., Lim, L.P., Burge, C.B., Bartel, B., Bartel, D.P. (2002). Prediction of plant microRNA targets. Cell, 110: 513–502.

    PubMed  CAS  Google Scholar 

  • Ruby, J.G., Calvin, H.J. and Bartel, D.P. (2007). Intronic microRNA precursors that bypass Drosha processing. Nature, 448: 83–86.

    PubMed  CAS  Google Scholar 

  • Ruegger, M., Dewey, E., Gray, W.M., Hobbie, L., Turner, J. and Estelle, M. (1998). TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p. Genes Dev., 12: 198–207.

    PubMed  CAS  Google Scholar 

  • Schwab, R., Palatnik, J.F., Riester, M., Schommer, C., Schmid, M. and Weigel, D. (2005). Specific effects of microRNAs on the plant transcriptome. Dev Cell., 8: 517–527.

    PubMed  CAS  Google Scholar 

  • Schwab, R., Ossowski, S., Riester, M., Warthmann, N. and Weigel, D. (2006). Highly specific gene silencing by artificial microRNAs in Arabidopsis. Plant Cell, 18: 1121–1133.

    PubMed  CAS  Google Scholar 

  • Schwarz, D.S., Hutvágner, G., Haley, B. and Zamore, P.D. (2002). Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell, 10: 537–548.

    PubMed  CAS  Google Scholar 

  • Sorin, C., Bussell, J.D., Camus, I., Ljung, K., Kowalczyk, M., Geiss, G., Mckhann, H., Garcion, C., Vaucheret, H., Sandberg, G. et al. (2005). Auxin and light control of adventitious rooting in Arabidopsis require ARGONAUTE1. Plant Cell, 17: 1376–1386.

    Google Scholar 

  • Spaepen, S., Vanderleyden, J. and Remans, R. (2007). Indole-3-acetic acid in microbial and microorganism-plant signaling FEMS Microbiol. Rev., 31: 425–448.

    CAS  Google Scholar 

  • Staswick, P.E., Serban, B., Rowe, M., Tiryaki, I., Maldonado, M.T., Maldonado, M.C., and Suza, W. (2005). Characterization of an Arabidopsis enzyme family that conjugates into amino acids to indole-3-acetic acid. Plant Cell., 17: 616–627.

    PubMed  CAS  Google Scholar 

  • Sunkar, R. and Zhu, J.K. (2004). Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis. Plant Cell., 16: 2001–2019.

    PubMed  CAS  Google Scholar 

  • Takada, S. Hibara K., Ishida, T. and Tasaka, M. (2001). The CUP-SHAPED COTYLEDON1 gene of Arabidopsis regulates shoot apical meristem formation. Development., 128: 1127–1135.

    PubMed  CAS  Google Scholar 

  • Tanaka, H., Dhonukshe, P., Brewer, P.B. and Friml, J. (2006). Spatiotemporal asymmetric auxin distribution: a means to coordinate plant development. Cell Mol. Life Sci., 63: 2738–2754.

    PubMed  CAS  Google Scholar 

  • Teale, W.D., Paponov, I.A. and Palme, K. (2006). Auxin in action: signalling, transport and the control of plant growth and development. Nat. Rev. Mol. Cell Biol., 7: 847–859.

    PubMed  CAS  Google Scholar 

  • Tian, C.E., Muto, H., Higuchi, K., Matamura, T., Tatematsu, K., Koshiba, T., and Yamamoto, K.T. (2004). Disruption and overexpression of auxin response factor 8 gene of Arabidopsis effect hypocotyls elongation and root growth habit, indicating its possible involvement in auxin homeostasis in light condition. Plant J., 40: 333–343.

    PubMed  CAS  Google Scholar 

  • Tiwari, S.B., Hagen, G., and Guilfoyle, T.J. (2004). Aux/IAA proteins contain a potent transcriptional repression domain. Plant Cell, 16: 533–543.

    PubMed  CAS  Google Scholar 

  • Tiwari, S.B., Hagen, G., and Guilfoyle, T. (2003). The roles of auxin response factor domains in auxin-responsive transcription. Plant Cell, 15: 533–543.

    PubMed  CAS  Google Scholar 

  • Ulmasov, T., Hagen, G. and Guilfoyle, T.J. (1999b). Dimerization and DNA binding of auxin response factors. Plant J., 19: 309–319.

    PubMed  CAS  Google Scholar 

  • Vazquez, F., Vaucheret, H., Rajagopalan, R., Lepers, C., Gasciolli, V., Mallory, A.C., Hilbert, J.L., Bartel, D.P. and Crete, P. (2004). Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. Mol Cell., 16: 69–79.

    PubMed  CAS  Google Scholar 

  • Vierstra, R.D. (2003). The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins. Trends Plant Sci., 8: 135–142.

    PubMed  CAS  Google Scholar 

  • Vieten, A., Sauer, M., Brewer, P.B. and Friml, J. (2007). Molecular and cellular aspects of auxin-transport-mediated development. Trends Plant Sci., 12: 160–168.

    PubMed  CAS  Google Scholar 

  • Wang, J.W., Wang, L.J., Mao, Y.B., Cai, W.J., Xue, H.W. and Chen, X.Y. (2005a). Control of root cap formation by MicroRNA-targeted auxin response factors in Arabidopsis. Plant Cell, 17: 2204–2216.

    PubMed  CAS  Google Scholar 

  • Wang, X., Zhang, J., Li, F., Gu, J., He, T., Zhang, X. and Li, Y. (2005b). MicroRNA identification based on sequence and structure alignment. Bioinformatics, 21: 3610–3614.

    PubMed  CAS  Google Scholar 

  • Wightman, B., Ha, I. and Ruvkun, G. (1993). Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell., 75: 855–862.

    PubMed  CAS  Google Scholar 

  • Williams, L., Grigg, S.P., Xie, M., Christensen, S. and Fletcher, J.C. (2005a). Regulation of Arabidopsis shoot apical meristem and lateral organ formation by microRNA miR166g and its AtHD-ZIP target genes. Development, 132: 3657–3668.

    PubMed  CAS  Google Scholar 

  • Williams, L., Carles, C.C., Osmont, K.S. and Fletcher, J.C. (2005b). A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes. Proc. Natl. Acad. Sci. USA, 102: 9703–9708.

    PubMed  CAS  Google Scholar 

  • Woodward, A.W. and Bartel, B. (2005). Auxin: Regulation, Action, and Interaction. Annals Bot., 95: 707–735.

    CAS  Google Scholar 

  • Xie, Q., Guo, H.-S., Dallman, G., Fang, S., Weissman, A.M. and Chua, N.-H. (2002). SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals. Nature, 419: 167–170.

    PubMed  CAS  Google Scholar 

  • Yang, L., Liu, Z., Lu, F., Dong, A. and Huang, H. (2006a). SERRATE is a novel nuclear regulator in primary microRNA processing in Arabidopsis. Plant J., 47: 841–850.

    PubMed  CAS  Google Scholar 

  • Yang, J.H., Han, S.J., Yoon, E.K. and Lee, W.S. (2006b) Evidence of an auxin signal pathway, microRNA167-ARF8-GH3, and its response to exogenous auxin in cultured rice cells. Nucleic Acids Res., 34: 1892–1899.

    PubMed  CAS  Google Scholar 

  • Zhang, H., Kolb, F.A., Jaskiewicz, L., Westhof, E. and Filipowicz, W. (2004). Single processing center models for human Dicer and bacterial RNase III. Cell, 118: 57–68.

    PubMed  CAS  Google Scholar 

  • Zhang B.H., Pan X.P., Wang, Q.L., Cobb, G.P. and Anderson, T.A. (2005). Identification and characterization of new plant microRNAs using EST analysis. Cell Res., 15: 336–360.

    PubMed  Google Scholar 

  • Zhang, B., Pan, X., Cobb, G.P. and Anderson, T.A. (2006a). Plant microRNA: a small regulatory molecule with big impact. Dev. Biol., 289: 3–16.

    PubMed  CAS  Google Scholar 

  • Zhang, B., Pan, X. and Anderson, T.A. (2006b). Identification of 188 conserved maize microRNAs and their targets. FEBS Lett., 580: 3753–3762.

    PubMed  CAS  Google Scholar 

  • Zhong, R. and Ye, Z.H. (2004). Amphivasal vascular bundle 1, a gain-of-function mutation of the IFL1/REV gene, is associated with alterations in the polarity of leaves, stems and carpels. Plant Cell Physiol., 45: 369–385.

    PubMed  CAS  Google Scholar 

  • Zhou, G.K., Kubo, M., Zhong, R., Demuram, T. and Ye, Z.H. (2007). Overexpression of miR165 affects apical meristem formation, organ polarity establishment and vascular development in Arabidopsis. Plant Cell Physiol., 48: 391–404.

    PubMed  CAS  Google Scholar 

Download references

Author information

Affiliations

  1. International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India

    Preeti Singh Teotia, Sunil Kumar Mukherjee & Neeti Sanan Mishra

Authors
  1. Preeti Singh Teotia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sunil Kumar Mukherjee
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Neeti Sanan Mishra
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Neeti Sanan Mishra.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Teotia, P.S., Mukherjee, S.K. & Mishra, N.S. Fine tuning of auxin signaling by miRNAs. Physiol Mol Biol Plants 14, 81–90 (2008). https://doi.org/10.1007/s12298-008-0007-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12298-008-0007-1

Key words

  • microRNAs
  • Biogenesis
  • Functions
  • Auxin
  • Plant development