Skip to main content
Log in

Investigating Investigation (Ab)Use: Thyroid Function Test Audit in a Tertiary Care Teaching Institute in Eastern India

  • Short Communication
  • Published:
Indian Journal of Clinical Biochemistry Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

An essential component of contemporary health care is laboratory testing. As the utilization of diagnostic tests grow, there is also an increase in the scrutiny of such tests for its effectiveness, balance of cost and over- utilization. Thyroid dysfunction is common across all age groups and is associated with a number of comorbid states. The thyroid function tests (TFTs) are very important for the diagnosis and monitoring of such patients. The guidelines recommend serum thyroid stimulating hormone (TSH) as the single most reliable test to diagnose all common forms of hypothyroidism and hyperthyroidism, except in few cases. This study was conducted to study the investigation requesting pattern of TFTs. Our results showed that TFT panel was ordered in almost equal numbers (35.58%) as single test of TSH (41.27%). Subclinical thyroid disease was diagnosed in 22.1% of cases and the rest were excluded as having any thyroid dysfunction. Over 2/3rd of all requests were for women. An important conclusion from our study was that, the essentiality of lab tests is a decision entirely in the hands of the treating physician keeping in mind the cost and best outcome for patients. Hospitals can develop strategic protocols for ordering laboratory tests keeping resources, need and patient satisfaction and outcomes optimal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Data Availability

Yes.

References:

  1. Rubinstein M, Hirsch R, Bandyopadhyay K, Madison B, Taylor T, Ranne A, et al. Effectiveness of practices to support appropriate laboratory test utilization. Am J Clin Pathol. 2018;149(3):197–221.

    Article  Google Scholar 

  2. Gilmour JA, Weisman A, Orlov S, Goldberg RJ, Goldberg A, Baranek H, et al. Promoting resource stewardship: reducing inappropriate free thyroid hormone testing. J Eval Clin Pract. 2017;23(3):670–5.

    Article  Google Scholar 

  3. Baral N, Koner BC, Lamsal M, Niraula I, Dhungel S. Thyroid function testing in eastern nepal and the impact of CME on subsequent requests. Trop Dr. 2001;31(3):155–7.

    CAS  Google Scholar 

  4. Gupta S, Verma M, Gupta AK, Kaur A, Kaur V, Singh K. Are we using thyroid function tests appropriately? Indian J Clin Biochem. 2011;26(2):178–81.

    Article  CAS  Google Scholar 

  5. Kluesner JK, Beckman DJ, Tate JM, Beauvais AA, Kravchenko MI, Wardian JL, et al. Analysis of current thyroid function test ordering practices. J Eval Clin Pract. 2018;24(2):347–52.

    Article  Google Scholar 

  6. Baskin HJ, Cobin RH, Duick DS, Gharib H, Guttler RB, Kaplan MM, et al. American association of clinical endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. Endocr Pract. 2002;8(6):457–69.

    Article  Google Scholar 

  7. Marot D, Maquart F-X, Delemer B, Decoudier B. Consistent, but totally misleading, thyroid function test results. Clin Chem. 2017;63(3):788–9.

    Article  CAS  Google Scholar 

  8. Sethi B, Barua S, Raghavendra MS, Gotur J, Khandelwal D, Vyas U. The thyroid registry: clinical and hormonal characteristics of adult Indian patients with hypothyroidism. Indian J Endocrinol Metab. 2017;21(2):302–7.

    Article  CAS  Google Scholar 

  9. Joshi SR. Laboratory evaluation of thyroid function. J Assoc Physicians India. 2011;59(Suppl):14–20.

    PubMed  Google Scholar 

  10. Kurian M, Kapoor N. Interpretation of thyroid function tests. Curr Med Issues. 2018;16(2):34.

    Article  Google Scholar 

  11. Ladenson PW, Singer PA, Ain KB, Bagchi N, Bigos ST, Levy EG, et al. American thyroid association guidelines for detection of thyroid dysfunction. Arch Intern Med. 2000;160(11):1573–5.

    Article  CAS  Google Scholar 

  12. Roti E, Gardini E, Magotti MG, Pilla S, Minelli R, Salvi M, et al. Are thyroid function tests too frequently and inappropriately requested? J Endocrinol Invest. 1999;22(3):184–90.

    Article  CAS  Google Scholar 

  13. Roy S, Bhattacharjee A, Mukherjee A, Jaisawal D, Das SN, Pal R. Cases referred for tests of thyroid function disorders at a tertiary care teaching hospital of Bihar: some experience. Indian J Public Health. 2006;50(4):236–8.

    CAS  PubMed  Google Scholar 

  14. Chauduri S, Roy A, Mukhergee A, Biswas AB. An analysis of cases referred for thyroid function disorder in a teaching hospital of Calcutta. Indian J Public Health. 1996;40(2):50–1.

    CAS  PubMed  Google Scholar 

  15. Roukema J, Steyerberg EW, van der Lei J, Moll HA. Randomized trial of a clinical decision support system: impact on the management of children with fever without apparent source. J Am Med Inform Assoc. 2008;15(1):107–13.

    Article  Google Scholar 

Download references

Acknowledgements

I acknowledge the help rendered by LiveHealth.solutions, Creliant Software Pvt Ltd., Pune for their support in retrieving and classification of TFTs from the Laboratory information system.

Funding

None.

Author information

Authors and Affiliations

Authors

Contributions

Dr. SS contributed in conceptualization, acquisition, analysis, interpretation of data, preparation and editing and Dr. JJ did the interpretation of data, review and editing of this manuscript. Both authors read and approved the final manuscript.

Corresponding author

Correspondence to Suchanda Sahu.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

IEC approval was obtained from our institute bearing the reference number T/IM-NF/ Biochem/18/ 19 DATED 15. 09. 2018.

Consent for Publication

We give consent to IJCB to publish this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sahu, S., John, J. Investigating Investigation (Ab)Use: Thyroid Function Test Audit in a Tertiary Care Teaching Institute in Eastern India. Ind J Clin Biochem 37, 499–503 (2022). https://doi.org/10.1007/s12291-020-00955-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12291-020-00955-w

Keywords

Navigation