Indian Journal of Clinical Biochemistry

, Volume 33, Issue 2, pp 235–238 | Cite as

Hypocalcemia Presenting as Life Threatening Torsades de Pointes with Prolongation of QTc Interval

  • Shibba Takkar Chhabra
  • Shivani Mehta
  • Sandeep Chhabra
  • Manikant Singla
  • Naved Aslam
  • Bishav Mohan
  • Gurpreet Singh Wander
Case Report


Torsades de pointes with prolonged QTc interval is a form of ventricular tachycardia. Many predisposing factors have been identified and hypocalcemia is among the rare ones. Our case illustrates that though rare, hypocalcemia might manifest as torsades de pointes with prolongation of QTc interval. Early diagnosis and management of dyselectrolytemia can prevent these patients from catastrophic torsades de pointes.


Hypocalcemia QTc interval prolongation Torsades de pointes 



Direct current


Blood pressure




Heart rate


Compliance with Ethical Standards

Conflict of interest



  1. 1.
    Cooper MS, Gittoes NJ. Diagnosis and management of hypocalcemia. BMJ. 2008;336:1298–302.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Roden DM. A practical approach to torsade de pointes. Clin Cardiol. 1997;20:285–90.CrossRefPubMedGoogle Scholar
  3. 3.
    Carter EP, Andrus EC. QT interval in human electrocardiogram in absence of cardiac disease. JAMA. 1922;78:19–22.Google Scholar
  4. 4.
    Schwartz PJ, Periti M, Malliani A. The long QT syndrome. Am Heart J. 1975;89:378–90.CrossRefPubMedGoogle Scholar
  5. 5.
    Moss AJ. Prolonged QT-interval syndromes. JAMA. 1986;256:2985–7 (Published erratum appears in JAMA 1987; 257:487).CrossRefPubMedGoogle Scholar
  6. 6.
    Eryol NK, Colak R, Ozdogru I, Tanriverdi F, Unal S, Topsakal R, et al. Effects of calcium treatment on QT interval and QT dispersion in hypocalcemia. Am J Cardiol. 2003;91:750–2.CrossRefPubMedGoogle Scholar
  7. 7.
    Bronsky D, Dubin A, Waldstein SS, Kushner DS. Calcium and the electrocardiogram. I. The electrocardiographic manifestations of hypoparathyroidism. Am J Cardiol. 1961;7:823–32.CrossRefGoogle Scholar
  8. 8.
    Ismail Z, Mohamed R, Hassan MHM, Wan SuK. Usage of traditional medicines among elderly and prednisolone contamination. MJMS. 2005;12:50–5.PubMedPubMedCentralGoogle Scholar
  9. 9.
    Patschan D, Loddenkemper K, Buttgereit F. Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone. 2001;29:498–505.CrossRefPubMedGoogle Scholar

Copyright information

© Association of Clinical Biochemists of India 2017

Authors and Affiliations

  • Shibba Takkar Chhabra
    • 1
  • Shivani Mehta
    • 2
  • Sandeep Chhabra
    • 3
  • Manikant Singla
    • 4
  • Naved Aslam
    • 1
  • Bishav Mohan
    • 1
  • Gurpreet Singh Wander
    • 1
  1. 1.Department of CardiologyDayanand Medical College and HospitalLudhianaIndia
  2. 2.Dayanand Medical College and HospitalLudhianaIndia
  3. 3.Department of MedicineDayanand Medical College and HospitalLudhianaIndia
  4. 4.Department of EndocrinologyDayanand Medical College and HospitalLudhianaIndia

Personalised recommendations