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Genetics of Obesity

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Abstract

Numerous classical genetic studies have proved that genes are contributory factors for obesity. Genes are directly responsible for obesity associated disorders such as Bardet–Biedl and Prader–Willi syndromes. However, both genes as well as environment are associated with obesity in the general population. Genetic epidemiological approaches, particularly genome-wide association studies, have unraveled many genes which play important roles in human obesity. Elucidation of their biological functions can be very useful for understanding pathobiology of obesity. In the near future, further exploration of obesity genetics may help to develop useful diagnostic and predictive tests for obesity treatment.

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This study was funded by DBT, New Delhi.

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Authors and Affiliations

  1. Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Rae Bareli Road, Lucknow, Uttar Pradesh, 226014, India

    Apurva Srivastava & Balraj Mittal

  2. Department of Physiology, King George’s Medical University, Chowk, Lucknow, Uttar Pradesh, 226003, India

    Apurva Srivastava & Neena Srivastava

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  1. Apurva Srivastava
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Correspondence to Balraj Mittal.

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Srivastava, A., Srivastava, N. & Mittal, B. Genetics of Obesity. Ind J Clin Biochem 31, 361–371 (2016). https://doi.org/10.1007/s12291-015-0541-x

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