Skip to main content
SpringerLink
Log in

Hyperemesis Gravidarum is a Syndrome of Metabolic and Endocrine Disturbances: A Case Description

  • Case Report
  • Published:
Indian Journal of Clinical Biochemistry Aims and scope Submit manuscript

Abstract

Hyperemesis gravidarum is a clinical syndrome characterized by excess vomiting, dehydration and weight loss associated high human chorionic gonadotropin levels, usually occurring in the first trimester of gestation. It often presents with severe electrolyte imbalance, mental confusion and may be associated with thyroid dysfunction. We are describing the management of one such case riddled with multiple metabolic events.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Bailit JL. Hyperemesis gravidarum: epidemiologic findings from a large cohort. Am J Obstet Gynecol. 2005;193:811.

    Article  PubMed  Google Scholar 

  2. Fell DB, Dodds L, Joseph KS, Allen VM, Butler B. Risk factors for hyperemesis gravidarum requiring hospital admission during pregnancy. Obstet Gynecol. 2006;107:277.

    Article  PubMed  Google Scholar 

  3. Verberg MFG, Gillot DJ, Al-Fardan N, Grudzinskas JG. Hyperemesis gravidarum, a literature review. Hum Reprod Update. 2005;11:527.

    Article  CAS  PubMed  Google Scholar 

  4. Chiossi G, Neri I, Cavazzuti M, Basso G, Facchinetti F. Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature. Obstet Gynecol Surv. 2006;61:255.

    Article  PubMed  Google Scholar 

  5. Kwan MC, Lee KF, Sin SY, Chan YW, Wong AKM. Wernicke’s encephalopathy in a patient with hyperemesis gravidarum and thyrotoxicosis. HKMJ. 1996;2:208–10.

    Google Scholar 

  6. Tan JY, Loh KC, Yeo GS, Chee YC. Transient hyperthyroidism of hyperemesis gravidarum. Br J Obstet Gynecol. 2002;109:683.

    Article  Google Scholar 

  7. Schmidt JA, Krause A, Feddersen CO, Kohl FV, Mariss G, Lütcke A, et al. Central pontine myelinolysis following severe hyponatremia. Klin Wochenschr. 1990;68(3):191–8.

    Google Scholar 

  8. Hagiwara K, Okada Y, Shida N, Yamashita Y. Extensive central and extrapontine myelinolysis in a case of chronic alcoholism without hyponatremia: a case report with analysis of serial MR findings. Intern Med. 2008;47(5):431–5.

    Article  PubMed  Google Scholar 

  9. Thompson PD, Gledhill RF, Quinn NP, Rossor MN, Stanley P, Coomes EN. Neurological complication associated with parenteral treatment: central pontine myelinolysis and Wernicke’s encephalopathy. BMJ. 1986;292:684–5.

    Google Scholar 

  10. Bernsen HJ, Prick MJ. Improvement of central pontine myelinolysis as demonstrated by repeated magnetic resonance imaging in a patient without evidence of hyponatremia. Acta Neurol Belg. 1999;99(3):189–93.

    CAS  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare that they have no conflict of interest to disclose.

Author information

Authors and Affiliations

  1. Department of Gynaecology and Obstetrics, Mamata Medical College/Mamata General Hospital (MMC/MGH), Khammam, India

    K. B. Gayathri

  2. Department of Endocrine and Metabolic Surgery, Mamata Medical College/Mamata General Hospital (MMC/MGH), Rotary Nagar, Khammam, 507002, Andhra Pradesh, India

    P. R. K. Bhargav

Authors
  1. K. B. Gayathri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. R. K. Bhargav
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to P. R. K. Bhargav.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gayathri, K.B., Bhargav, P.R.K. Hyperemesis Gravidarum is a Syndrome of Metabolic and Endocrine Disturbances: A Case Description. Ind J Clin Biochem 29, 390–392 (2014). https://doi.org/10.1007/s12291-013-0384-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12291-013-0384-2

Keywords

Search

Navigation