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Effect of Lipid Profile Upon Prognosis in Ischemic and Haemorrhagic Cerebrovascular Stroke

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Abstract

Stroke is the third major cause of death worldwide. Elevated plasma concentration of low density lipoproteins and low plasma concentration of high density lipoprotein concentration are associated with an increased risk of atherosclerosis and coronary heart disease but the relation between serum lipids, and cerebrovascular disease is less clear. The aim of this study was to investigate the reliability and accuracy of serum lipid profile in assessing the prognosis/neurological worsening in patients with ischemic and hemorrhagic cerebrovascular stroke. The subjects in the present study comprised of 101 healthy controls and 150 cerebrovascular stroke patients (including 90 with ischemic stroke and 60 with intracerebral hemorrhagic stroke). In both the groups fasting lipid profile was determined within 72 h of the stroke. A statistically significant association was observed (p < 0.001) between the parameters of lipid profile of cases and healthy controls, and also with the prognosis of the stroke.

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Authors and Affiliations

  1. Department of Biochemistry, Chirayu Medical College, Bhopal, India

    Anuradha Bharosay

  2. Department of Pathology, Chirayu Medical College, Bhopal, India

    Vivek V. Bharosay

  3. Department of Biochemistry, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar, 751019, India

    Debapriya Bandyopadhyay

  4. Department of Neurology, Sri Aurobindo Institute of Medical Sciences, Indore, India

    Ajoy Sodani

  5. Department of Biochemistry, Sri Aurobindo Institute of Medical Sciences, Indore, India

    Meena Varma

  6. Department of Biochemistry, Subharti Medical College, Meerut, India

    Haren Baruah

Authors
  1. Anuradha Bharosay
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  2. Vivek V. Bharosay
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  3. Debapriya Bandyopadhyay
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  4. Ajoy Sodani
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  5. Meena Varma
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  6. Haren Baruah
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Correspondence to Debapriya Bandyopadhyay.

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Bharosay, A., Bharosay, V.V., Bandyopadhyay, D. et al. Effect of Lipid Profile Upon Prognosis in Ischemic and Haemorrhagic Cerebrovascular Stroke. Ind J Clin Biochem 29, 372–376 (2014). https://doi.org/10.1007/s12291-013-0372-6

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  • DOI: https://doi.org/10.1007/s12291-013-0372-6

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