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Evaluation of Sickle Cell Module for Quality of Life in Egyptian Children and Adolescents Patients: Impact of Psychiatric and Disease Specific Variables

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Sickle cell disease (SCD) impacts the physical, emotional, and psychological aspects of life. We aimed to study the quality of life (QoL) in Egyptian children and adolescents with SCD using the sickle cell module in relations to social, psychological and disease variables. A cross sectional study included 40 patients with SCD between 5 and 18 years. Details of diagnosis, SCD related complications, socioeconomic status were revised. Psychological assessment was done using children depression inventory, revised Children's Manifest anxiety scale and Health related QoL for both patients and parents using a validated Arabic age specific version of sickle cell module. Significant better scores for communication problems in mothers with college degree was found compared with other academic levels with no significant difference in QoL in relation to father education and significant higher communication problems with high rate of hospitalization (P = .021). Pain score was higher in 8–13 years compared with 13–18 years age groups. Significant worse scores for worrying was found in females, P = 0.033; Depression was found in 90% of studied patients. The main determinants of QoL in patients with SCD were maternal education and frequency of hospitalization. Depression is of alarming frequency for intervention.

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Abbreviations

QoL:

Quality of Life

SCD:

Sickle cell disease

CDI:

Children depression inventory

RCMAS:

Revised children's manifest anxiety scale

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Authors and Affiliations

  1. Paediatric Department, Hematology-Oncology Unit, Faculty of Medicine, Ain Shams University, Cairo, Egypt

    Iman Ahmed Ragab, Mohamed Abdel-Mohsen Ellabody, Naglaa Fathy Mahmoud & Safa Matbouly Sayed

  2. Neuropsychiatry Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

    Hisham Ahmed Ramy

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  1. Iman Ahmed Ragab
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  2. Mohamed Abdel-Mohsen Ellabody
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  3. Hisham Ahmed Ramy
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  4. Naglaa Fathy Mahmoud
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  5. Safa Matbouly Sayed
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Correspondence to Iman Ahmed Ragab.

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Ragab, I.A., Ellabody, M.AM., Ramy, H.A. et al. Evaluation of Sickle Cell Module for Quality of Life in Egyptian Children and Adolescents Patients: Impact of Psychiatric and Disease Specific Variables. Indian J Hematol Blood Transfus 37, 616–622 (2021). https://doi.org/10.1007/s12288-021-01396-y

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  • DOI: https://doi.org/10.1007/s12288-021-01396-y

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