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Application of Perioperative Transfusion Trigger Score in Patients Undergoing Surgical Treatment of Malignant Tumor

Indian Journal of Hematology and Blood Transfusion volume 36, pages 156–163 (2020)Cite this article

Abstract

The present study aimed to investigate the clinical effects of the brand new perioperative transfusion trigger score (POTTS) system in patients undergoing malignant tumor surgeries. 442 cases of patients diagnosed with malignant tumor were randomly selected (from January 2012 to December 2016) from Zunyi Medical University and were divided into 3 experimental groups. Patients in the POTTS group were transfused by the POTTS guideline perioperatively, while patients in the 7–10 g group were treated by the traditional transfusion guidelines existed (restrictive transfusion strategy), patients in the 10 g group should be transfused to keep the Hb level no less than 10 g/dL (liberal transfusion strategy). Baseline information, operation time, bleeding volume, transfusion amount, incision healing time, postoperative complications, metastasis and recurrence were observed and recorded. Postoperative short-term mortality was comparable of the 3 groups, 3 cases of death all occurred in 10 g group, there was no significant difference in the incidence of postoperative complications, including infectious complications and coagulation related complications. Follow-up to date, there were 25 cases, 29 cases and 29 cases of tumor recurrence and metastasis in the three groups, but no statistical difference observed. The present findings show that the POTTS transfusion system is more advantageous with regard to save blood and relieve economic burdens of patients, and does not affect the long-term recurrence and metastasis rate of malignant tumor.

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Acknowledgements

The present authors would like to acknowledge all the authors of the original studies included in the study.

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Affiliations

  1. Department of Anesthesiology, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, People’s Republic of China

    Fan Zhang, Zhao-Qiong Zhu & De-Xing Liu

  2. Department of Pediatric Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, People’s Republic of China

    Ze-Bing Zheng

  3. Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People’s Republic of China

    Jin Liu

  4. Department of Anesthesiology, Zunyi Medical University, Zunyi, 563003, Guizhou, People’s Republic of China

    Fan Zhang

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  1. Fan Zhang
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  2. Ze-Bing Zheng
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  3. Zhao-Qiong Zhu
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  4. De-Xing Liu
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  5. Jin Liu
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Correspondence to Fan Zhang.

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Zhang, F., Zheng, ZB., Zhu, ZQ. et al. Application of Perioperative Transfusion Trigger Score in Patients Undergoing Surgical Treatment of Malignant Tumor. Indian J Hematol Blood Transfus 36, 156–163 (2020). https://doi.org/10.1007/s12288-019-01180-z

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  • DOI: https://doi.org/10.1007/s12288-019-01180-z

Keywords

  • POTTS
  • Transfusion
  • Malignant tumor
  • Prognosis