Impact Analysis of the National Guidelines for Blood Donor Selection in India: A Single Center Study


National Blood Transfusion Council recently released the national guidelines for blood donor selection in India. Some changes in the currently used donor selection criteria have been proposed. However, its effect on future donor availability and deferral has not been studied. To enumerate the changes in current donor selection criteria and analyze its impact on the future blood donor availability vis-à-vis current deferral rate. One year data for both selected and deferred whole blood donors was analyzed retrospectively. Questionnaire forms of the selected donors were screened to analyze the responses given at the time of donation. A total of 4494 donors presented for whole blood donation and 995 (22.1%) were deferred for the various reasons. NBTC has proposed 12 major changes in the currently used donor selection criteria with 11 resulting into increased deferral of the blood donors. These changes would lead to an additional deferral of 32.5% of the currently eligible blood donors mostly due to the change in the blood pressure cut off. National blood donor selection guidelines in the current form would lead to a very high deficit of available blood donors in India. There is an urgent need to reconsider the merit of the changes suggested in these guidelines.

This is a preview of subscription content, log in to check access.


  1. 1. New Delhi. National Blood Transfusion Council. Accessed 15 Nov 2018

  2. 2.

    National Accreditation Board for Hospitals and Healthcare Providers (NABH) (2016) Accreditation standards on blood banks/blood centers and transfusion services, 3rd edn. NABH, New Delhi

    Google Scholar 

  3. 3.

    Blood donor selection: guidelines on assessing donor suitability for blood donation. World Health Organization 2012.

  4. 4.

    Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India (2003) Transfusion Medicine Technical Manual, 2nd edn. Directorate General of Health Services, New Delhi

    Google Scholar 

  5. 5.

    Offergeld Ruth, Heiden Margarethe (2017) Selecting the right donors-still a challenge: development of a uniform donor questionnaire in Germany. Transfus Med Hemother 44:255–262

    Article  Google Scholar 

  6. 6.

    Sundar P, Sangeetha SK, Seema DM, Marimuthu P, Shivanna N (2010) Pre-donation deferral of blood donors in South Indian set-up: an analysis. Asian J Transfus Sci 4(2):112–115

    CAS  Article  Google Scholar 

  7. 7.

    Chourdary RK, Gupta D, Gupta RK (1995) Analysis of donor-deferral pattern in a voluntary blood donor population. Transfus Med 5:209–212

    Article  Google Scholar 

  8. 8.

    Unnikrishnan B, Rao P, Kumar N, Ganti S, Prasad R, Amarnath A et al (2011) Profile of blood donors and reasons for deferral in coastal South India. Australas Med J 4:379–385

    CAS  Article  Google Scholar 

  9. 9.

    Bahadur S, Jain S, Goel RK, Pahuja S, Jain M (2009) Analysis of blood donor deferral characteristics in Delhi, India. Southeast Asian J Trop Med Public Health 40:1087–1091

    PubMed  Google Scholar 

  10. 10.

    Sharma T, Singh B, Bhatt GC (2013) Profile of deferral of blood donors in regional blood transfusion center in North India. Asian J Transfus Sci 7:163–164

    Article  Google Scholar 

  11. 11.

    Agnihotri N (2010) Whole blood donor deferral analysis at a center in Western India. Asian J Transfus Sci 4:116–122

    CAS  Article  Google Scholar 

  12. 12.

    Zou Shimian, Musavi Fatemeh, Notari Edward P, Rios Jorge A, Trouern-Trend Jonathan, Fang Chyang T (2008) Donor deferral and resulting donor loss at the American Red Cross Blood Services, 2001 through 2006. Transfusion 48:2531–2539

    Article  Google Scholar 

  13. 13.

    Travasso C (2016) India draws a red line under antibiotic misuse. BMJ 29:352

    Google Scholar 

  14. 14.

    Porter G, Grills N (2016) Medication misuse in India: a major public health issue in India. J Public Health 38:e150–e157

    Article  Google Scholar 

  15. 15.

    Trouern-Trend JJ, Cable RG, Badon SJ, Newman BH, Popovsky MA (1999) A case-controlled multi-center study of vasovagal reactions in donors: influence of sex, age, donation status, weight, blood pressure and pulse. Transfusion 39(3):316–320

    CAS  Article  Google Scholar 

  16. 16.

    Stainsby D, Brunskill S, Chapman CE, Dorée C, Stanworth S (2010) Safety of blood donation from individuals with treated hypertension or non-insulin dependent type 2 diabetes—a systematic review. Vox Sang 98(3):431–440

    CAS  Article  Google Scholar 

  17. 17.

    National Blood Service, United Kingdom (2013) Guidelines for the blood transfusion services in the United Kingdom, 8th edn. TSO (The stationary office), London.

  18. 18.

    American Association of Blood Banks (2016) Standards for Blood Banks and Transfusion Services, 30th edn. AABB, Bethesda

    Google Scholar 

Download references

Author information




Naveen Agnihotri planned the study, analyzed the data and designed the manuscript. Ajju Agnihotri & Yatendra Mohan conducted the research, prepared the data and assisted in the manuscript.

Corresponding author

Correspondence to Naveen Agnihotri.

Ethics declarations

Conflict of interest

No conflict of interest by any of the authors.

Research Involving Human Participants and/or Animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Agnihotri, N., Chaturvedi, Y.M. & Agnihotri, A. Impact Analysis of the National Guidelines for Blood Donor Selection in India: A Single Center Study. Indian J Hematol Blood Transfus 35, 726–730 (2019).

Download citation


  • NBTC guidelines
  • Whole blood donor selection
  • Donor deferral