Abstract
A 32-years-old male developed exfoliating skin lesions in bilateral axillae and groins on D-42 post matched sibling allogeneic transplant. These lesions masqueraded betadine burns with a positive history of betadine application in the affected regions. He gradually developed lesions involving other parts of the body with Glucksberg grade-IV acute GVHD (skin-stage: IV/gut-stage: III). He succumbed to his illness. We present this case to highlight the rare initial presentation of skin GVHD involving localized body regions with sparing of rest of the body and mimicking betadine burns.
References
Peñas PF, Zaman S (2010) Many faces of graft-versus-host disease. Australas J Dermatol 51(1):1–10; quiz 11. doi:10.1111/j.1440-0960.2009.00577.x. Review. PubMed PMID: 20148830
Mays SR, Kunishige JH, Truong E, Kontoyiannis DP, Hymes SR (2007) Approach to the morbilliform eruption in the hematopoietic transplant patient. Semin Cutan Med Surg 26(3):155–162. Review. PubMed PMID: 18070682
Abu-Dalle I, Reljic T, Nishihori T, Antar A, Bazarbachi A, Djulbegovic B, Kumar A, Kharfan-Dabaja MA (2014) Extracorporeal photopheresis in steroid-refractory acute or chronic graft-versus-host disease: results of a systematic review of prospective studies. Biol Blood Marrow Transplant. 20(11):1677–1686. PubMed PMID: 24867779
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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The work is to be attributed at Department of Clinical Haematology and Internal Medicine, P.G.I.M.E.R, Chandigarh, U.T 160012, India.
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Yanamandra, U., Nahar Saikia, U., Prakash, G. et al. Skin GVHD Mimicking Betadine Rash in a Post Allogeneic Transplant Patient. Indian J Hematol Blood Transfus 33, 427–430 (2017). https://doi.org/10.1007/s12288-016-0750-3
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DOI: https://doi.org/10.1007/s12288-016-0750-3