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Congenital Dyserythropoietic Anemia Type 1: Report of One Patient and Analysis of Previously Reported Patients Treated with Interferon Alpha

Abstract

Congenital dyserythropoietic anemias are a rare group of inherited anemias characterized by ineffective erythropoiesis and distinct morphological abnormalities in the erythroblasts. Interferon alpha has been shown to be effective in type 1 congenital dyserythropoietic anemia but the optimal duration of therapy is undefined. We present here a 32-years-old female patient diagnosed with type 1 congenital dyserythropoietic anemia precipitated by pregnancy and treated successfully with a short course of interferon alpha resulting in a durable response. A literature search including PubMed database on previously published articles regarding congenital dyserythropoietic anemia type 1 patients treated with interferon is conducted.

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Correspondence to Ayse Salihoglu.

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Salihoglu, A., Elverdi, T., Eskazan, A.E. et al. Congenital Dyserythropoietic Anemia Type 1: Report of One Patient and Analysis of Previously Reported Patients Treated with Interferon Alpha. Indian J Hematol Blood Transfus 32, 272–277 (2016). https://doi.org/10.1007/s12288-015-0600-8

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Keywords

  • Brucellosis
  • Paroxysmal Nocturnal Hemoglobinuria
  • Deferasirox
  • Extramedullary Hematopoiesis
  • Ringed Sideroblasts