Current Role of Genetics in Hematologic Malignancies

  • Gaurav Prakash
  • Anupriya KaurEmail author
  • Pankaj Malhotra
  • Alka Khadwal
  • Prashant Sharma
  • Vikas Suri
  • Neelam Varma
  • Subhash Varma
Review Article


Rapidly changing field of genetic technology and its application in the management of hematological malignancies has brought significant improvement in treatment and outcome of these disorders. Today, genetics plays pivotal role in diagnosis and prognostication of most hematologic neoplasms. The utilization of genetic tests in deciding specific treatment of various hematologic malignancies as well as for evaluation of depth of treatment response is rapidly advancing. Therefore, it is imperative for practitioners working in the field of hemato-oncology to have sufficient understanding of the basic concepts of genetics in order to comprehend upcoming molecular research in this area and to translate the same for patient care.


Hematology Oncology Genetics Molecular tests 



We acknowledge Department of Hematology, PGIMER, Chandigarh for providing images for this publication.

Compliance with Ethical Standards

Conflict of interest

There are no potential conflicts of interest of authors writing this article.

Research involving human participants and/or animals

This is a review article and does not involve any human or animal intervention or experiment.

Informed consent

No human subjects or biologic material was used for this review article.


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Copyright information

© Indian Society of Haematology & Transfusion Medicine 2015

Authors and Affiliations

  • Gaurav Prakash
    • 1
  • Anupriya Kaur
    • 2
    Email author
  • Pankaj Malhotra
    • 1
  • Alka Khadwal
    • 1
  • Prashant Sharma
    • 3
  • Vikas Suri
    • 1
  • Neelam Varma
    • 3
  • Subhash Varma
    • 1
  1. 1.Clinical Hematology and BMT Division, Department of Internal MedicinePGIMERChandigarhIndia
  2. 2.Medical Geneticist, Sarai BuildingGovernment Medical CollegeChandigarhIndia
  3. 3.Department of HematologyPGIMERChandigarhIndia

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