Frequency of West Nile Virus Infection in Iranian Blood Donors


West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.

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The authors would like to thank the Research Center of the IBTO and Queensland University of Technology, Australia for supporting this study. We also wish to express our thanks to all employees of the QC laboratory of the IBTO who have been a great source of inspiration and technical expertise.

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Correspondence to Afsaneh Aghaie.

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The authors declare that there is no conflict of interest.

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Communicated by Haraprasad Pati.

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Aghaie, A., Aaskov, J., Chinikar, S. et al. Frequency of West Nile Virus Infection in Iranian Blood Donors. Indian J Hematol Blood Transfus 32, 343–346 (2016).

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  • West Nile virus (WNV)
  • Blood donor
  • Iran
  • Donor selection
  • Epidemiology
  • Enzyme linked immune sorbent assay (ELISA)
  • Immunoflouorescence assay (IFA)