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Hemophagocytosis by Leukemic Blasts in T Cell Acute Lymphoblastic Leukemia: An Unusual Finding

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Abstract

Hemophagocytosis shows engulfment of hematopoietic cells by histiocytes and is a property generally associated with cells of the histiocytic lineage. It can be familial or is seen in a wide spectrum of acquired disorders. Hemophagocytosis by leukemic blasts is an uncommon phenomenon and has been reported mainly in acute myeloid leukemia. Its association with acute lymphoblastic leukemia is rare. We present a case of hemophagocytosis by blasts in the bone marrow in a 11 year old boy with T cell-acute lymphoblastic leukemia.

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Authors and Affiliations

  1. Department of Pathology, Christian Medical College & Hospital, Brown Road, Ludhiana, 141 008, Punjab, India

    Aradhana Harrison, Dinesh Chandra, Naveen Kakkar & Sheila Das

  2. Department of Clinical Hematology, Hemato-Oncology and Bone Marrow (Stem cell), Transplant Unit, Christian Medical College & Hospital, Brown Road, Ludhiana, 141 008, Punjab, India

    M. Joseph John

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  1. Aradhana Harrison
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  2. Dinesh Chandra
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  3. Naveen Kakkar
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  4. Sheila Das
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  5. M. Joseph John
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Correspondence to Naveen Kakkar.

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Harrison, A., Chandra, D., Kakkar, N. et al. Hemophagocytosis by Leukemic Blasts in T Cell Acute Lymphoblastic Leukemia: An Unusual Finding. Indian J Hematol Blood Transfus 32 (Suppl 1), 23–25 (2016). https://doi.org/10.1007/s12288-015-0531-4

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  • DOI: https://doi.org/10.1007/s12288-015-0531-4

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