Abstract
B cell chronic lymphocytic leukemia (CLL) also called chronic lymphocytic leukemia is a disease of elderly, but in rare cases it can occur in young adults. Majority of patients present with no specific symptoms, and CLL is suspected on the basis of high total and relative lymphocyte counts, discovered on routine blood examination. This patient was referred from medicine outpatient in our institute, Era’s Lucknow Medical College & Hospital for routine complete blood count. His total leukocyte count came out to be alarmingly high. The general blood picture and bone marrow examinations were consistent with CLL. On immunophenotyping CD5 and CD23 were positive. His cervical lymph nodes biopsy was reported as a case of CLL/small lymphocytic lymphoma. On his complaint of hazy vision his funduscopy revealed maculopathy. This makes our case a unique and rare one, as maculopathy in a young patient of CLL has not yet been reported from India.
References
Spier CM, Kjeldsberg CR, Head DR, DiFiore KC, Tudor B (1985) Chronic lymphocytic leukemia in young adults. Am J Clin Pathol 84(5):675–678
Vyas N, Hassan A (2012) Recent advances in chronic lymphocytic leukemia. Indian J Cancer 49(1):137–143
Davies CE, Whitelocke RA, Agrawal S (2008) Retinal complications associated with hyperviscosity in chronic lymphocytic leukaemia. Intern Med J. 38(2):140
Levy-Clarke GA, Greenman D, Sieving PC, Byrnes G, Shen D, Nussenblatt R, Chan CC (2008) Ophthalmic manifestations, cytology, immunohistochemistry, and molecular analysis of intraocular metastatic T-cell lymphoma: report of a case and review of the literature. Surv Ophthalmol 53(3):285–295
Calfa CJ, Lossos IS, Ruiz P, Davis JL (2007) Ocular involvement as the initial manifestation of T-cell chronic lymphocytic leukemia. Am J Ophthalmol 144(2):326–329
Kanski JJ (2007) Clinical ophthalmology: a systemic approach. 6th edition
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Mehdi, S.R., Tandon, N., Khan, S.A. et al. A Case of Early Ocular Manifestation of Maculopathy in a 37 year Old Male Patient of CLL. Indian J Hematol Blood Transfus 30 (Suppl 1), 341–345 (2014). https://doi.org/10.1007/s12288-014-0399-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12288-014-0399-8