Microfilariae with Acute Myeloid Leukemia: A Common Parasite with Uncommon Association


Presence of microfilariae in bone marrow aspirate is an uncommon finding and its association with leukaemia has rarely been described. We present a case of young female from north India in which bancroftian microfilariae was seen in peripheral blood and bone marrow smears as an incidental finding along with 88 % myeloid blast that were positive on myeloperoxidase stain. There was no associated eosinophilia. She was started on diethylcarbazine for microfilariae, before the start of induction chemotherapy for acute myeloid leukaemia. Presently she is post induction and is doing fine.

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  1. 1.

    Gupta S, Gupta R, Bansal B, Singh S, Gupta K, Kudesia M (2009) Significance of incidental detection of filariasis on aspiration smears: a case series. Diagn Cytopathol 11(38(7)):517–520

    Article  Google Scholar 

  2. 2.

    Ahmad SS, Hassan MJ, Akhtar K, Arif SH, Naim M, Rahman K (2008) Microfilariae in testicular fine needle aspiration biopsy. JK Sci 10(4):199–200

    Google Scholar 

  3. 3.

    Zafar U, Rahman K, Sherwani RK, Shahid M (2008) Microfilariae of Wuchereria bancrofti in bone marrow. Indian J Hematol Blood Transfus 25(1):42–43

    Article  Google Scholar 

  4. 4.

    Sharma S, Rawat A, Chouhan A (2006) Microfilariae, in bone marrow aspiration smear, correlation with marrow hypoplasia: a report in six cases. Indian J Pathol Microbial 49(4):556–558

    Google Scholar 

  5. 5.

    Pradhan S, Lahiri VL, Ethence BR, Singh KN (1976) Micorfilariae of Wuchereria bancrofti in bone marrow smear. Am J Trop Med Hyg 25(1):199–200

    PubMed  CAS  Google Scholar 

  6. 6.

    Sharma P, Tyagi S (2010) An unusual cause of eosinophilia in AML-M4 without the Inv(16) abnormality. J Blood Disord Transfus 1:104

    Google Scholar 

  7. 7.

    Jain S, Dass J, Sharma M, Tyagi S (2011) Common parasite with uncommon association. Mediterr J Hematol Infect Dis 3. doi:10.4084/MJHID.2011.015

    PubMed  Article  Google Scholar 

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Correspondence to Khaliqur Rahman.

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Rahman, K., George, S., Sardana, M. et al. Microfilariae with Acute Myeloid Leukemia: A Common Parasite with Uncommon Association. Indian J Hematol Blood Transfus 29, 113–115 (2013). https://doi.org/10.1007/s12288-012-0154-y

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  • Acute myeloid leukaemia
  • Microfilariae