Skip to main content

Pure Red Cell Aplasia in Systemic Onset Juvenile Idiopathic Arthritis

Indian Journal of Hematology and Blood Transfusion volume 28, pages 42–43 (2012)Cite this article

Abstract

Common causes of anemia in juvenile idiopathic arthritis are anemia of chronic disease and iron deficiency. We report a 4 year old boy with biopsy proven systemic onset juvenile idiopathic arthritis and severe anemia. Bone marrow aspiration revealed pure red cell aplasia without evidence of hemophagocytosis. This rare, unexplained but well known entity responded to corticosteroids.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  1. Ravindran V, Jain S, Mathur DS (2008) The differentiation of anaemia in rheumatoid arthritis: parameters of iron deficiency in an Indian rheumatoid arthritis population. Rheumatol Int 28(6):507–511

    PubMed  Article  CAS  Google Scholar 

  2. Rubin RN, Walker BK, Ballas SK, Travis FS (1978) Erythroid aplasia in juvenile rheumatoid arthritis. Am J Dis Child 132(8):760–762

    PubMed  CAS  Google Scholar 

  3. Singh RR, Malviya AN, Kapoor SK, Pati H (1990) Pure red cell aplasia with rheumatoid arthritis. A case report, review of literature. J Assoc Physicians India 38(3):233–235

    PubMed  CAS  Google Scholar 

  4. Agarwal V, Sachdev A, Lehl S (2004) Unusual hematological alterations in rheumatoid arthritis. J Postgrad Med 50:60–61

    PubMed  CAS  Google Scholar 

  5. Ewer K, Darbyshire PJ, Southwood TR (1993) Systemic onset juvenile chronic arthritis and bone marrow hypoplasia. Br J Rheumatol 32:78–80

    PubMed  Article  CAS  Google Scholar 

  6. Sinha AK, Agarwal A, Lakhey M (2003) Pure red cell aplasia-report of 11 cases from Eastern Nepal. Indian J Pathol Microbiol 46(3):405–408

    PubMed  Google Scholar 

  7. Prouse PeterJ, Andrew R (1987) Harvey, Brian Bonner. Anaemia in juvenile chronic arthritis: serum inhibition of normal erythropoiesis in vitro. Ann Rheum Dis 46:127–134

    PubMed  Article  CAS  Google Scholar 

  8. Dessypris EN, Baer MR, Sergent JS, Krantz SB (1984) Rheumatoid arthritis, pure red cell aplasia. Ann Intern Med 100(2):202–206

    PubMed  CAS  Google Scholar 

  9. Kamper AM, Malbrain M, Zachee P, Chew SL (1994) Parvovirus infection causing red cell aplasia and leukopenia in rheumatoid arthritis. Clin Rheumatol 13(1):129–131

    PubMed  Article  CAS  Google Scholar 

  10. Huang JL, Hung IJ, Chen LC (1998) Successfully treated sulphasalazine-induced fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia with intra venous immunoglobulin. Clin Rheumatol 17(4):349–352

    PubMed  Article  CAS  Google Scholar 

  11. Tishler M, Kahn Y, Yaron M (1991) Pure red cell aplasia caused by D-penicillamine treatment of rheumatoid arthritis. Ann Rheum Dis 50(4):255–256

    PubMed  Article  CAS  Google Scholar 

  12. Ustün C, Karavelioğlu D, Ilhan O (1997) A case report of a patient who has pure red cell aplasia and rheumatoid arthritis. Int J Hematol 66(4):505–512

    PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Affiliations

  1. Department of Pediatrics, Government Medical College, Thrissur, Kerala, India

    Priya Sreenivasan & N. S. Mani

Authors
  1. Priya Sreenivasan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. S. Mani
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Priya Sreenivasan.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Sreenivasan, P., Mani, N.S. Pure Red Cell Aplasia in Systemic Onset Juvenile Idiopathic Arthritis. Indian J Hematol Blood Transfus 28, 42–43 (2012). https://doi.org/10.1007/s12288-011-0085-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12288-011-0085-z

Keywords

  • Systemic onset juvenile idiopathic arthritis
  • Pure red cell aplasia