References
Kumar S, Noronha V, Chu E (2005) Antimetabolites. In Cancer: Principles and Practice of Oncology. 7th Edition. Vincent T DeVita Jr, Samuel Heltman, Steven A Rosenberg (eds) Lippincott Williams & Wilkins. pp 360–361
Rubinstein LJ, Herman MM, Long TF, Wilbur JR (1975) Disseminated necrotizing leukoencephalopathy: a complication of treated central nervous system leukemia and lymphoma. Cancer 35:291–305
Davidson A, Payne G, Leach MO, et al. (2000) Proton magnetic resonance spectroscopy of the brain following high-dose methotrexate treatment for childhood cancer. Med Pediatr Oncol 35:28–34
Quinn CT, Griener JC, Bottiglieri T, et al. (1997) Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer. J Clin Oncol 15:2800–2806
Fisher MJ, Khademian ZP, Simon EM et al. (2005) Diffusion-weighted MR imaging of early methotrexate-related neurotoxicity in children. Am J Neuroradiol 26:1686–1689
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Cyriac, S., Rajendranath, R. & Sagar, T.G. Early CNS toxicity after intrathecal methotrexate. Indian J Hematol Blood Transfus 24, 186–187 (2008). https://doi.org/10.1007/s12288-008-0045-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12288-008-0045-4