Abstract
T-cell Prolymphocytic Leukemia (T-PLL) is a mature post-thymic T-cell malignancy with aggressive clinical course. The principal disease characteristics are organomegaly, skin lesions and raised lymphocyte counts. We report two cases of T-PLL. T-PLL is a rare T-cell malignancy with characteristic clinical and laboratory features and a poor prognosis. It needs to be differentiated from B-Cell prolymphocytic leukemia (B-PLL) and other mature T-cell lymphoproliferative disorders with predominant leukemic pattern. Differentiation can be made by a comprehensive approach taking into account the clinical features, the cell morphology and the immunophenotype of leukemic cells.
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Naseem, S., Gupta, R., Kashyap, R. et al. T-cell prolymphocytic leukemia: a report of two cases with review of literature. Indian J Hematol Blood Transfus 24, 178–181 (2008). https://doi.org/10.1007/s12288-008-0043-6
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DOI: https://doi.org/10.1007/s12288-008-0043-6