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Flow cytometry in acute leukemia

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Immunophenotyping of acute leukemia is one of the most important clinical application of Flow cytometery. The aim of this work is to review recent advances in flow cytometery methods, quality control, troubleshooting and its prevention and data analysis of acute leukemia. Multiparameter flow cytometery is a useful adjunct to morphology and cytochemistry and it is an invaluable tool in the diagnosis of acute leukemia.

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References

  1. Craig FE, Foon KA (2008) Flow cytometeric immunophenotyping for hematologic neoplasms. Blood 111:3941–3967

    Article  PubMed  CAS  Google Scholar 

  2. Lewis SM, Bain BJ, Bates I (eds) Dacie and lewis. Practical Haematology Churchill living strone Philadelphia 335–355

  3. Nagugen D, Diamond LW, Braylan RC (2003) Flwocytometery in Hematopathology: a visual approach to data analysis and interpretation. Humana Press New Jersey

    Google Scholar 

  4. Pagnucco G, Vanelliard L, Gervasi F (2002) Multidimentional flow cytometery immunophenotyping of hematolgical malignancy. Annals NY Acad Sci 963:313–321

    Article  Google Scholar 

  5. Weir EG, Borowitz MJ (2001) Flow cytometery in the diagnosis of acute leukemia. Seminars in hematology 38: 124–138

    Article  PubMed  CAS  Google Scholar 

  6. Huh YD, Ibrahm S (2000) Immunophenotyping in adult acute lymphoblastic leukemia role of flow cytometery in diagnosis and monitoring of diseases. Hemtology/Oncology Clinics of North America 14:1251–1264

    Article  CAS  Google Scholar 

  7. Bruning RD, Head D, Matutes E, Vardiman J, Borowitz M, Bennett J et al (2001) Acute leukemia of ambiguous lineage. IN: Jaffe ES, Harris NL, Stein H, Vardiman JW (eds). World Health Organization classification of tumors, pathology and genetics of tumors of haematopoietic lymphoid tissues. IARC Press: Lyon, France, pp 106–107

    Google Scholar 

  8. Weir EG, Ali Ansari M, Batista DAS et al. (2007) Acute bilineal leukemia: a rare diagse with poor outcome. Leukemia 21: 2264–2270

    Article  PubMed  CAS  Google Scholar 

  9. Bene MC, Castoldi G, Knapp W, Ludwig WD, Matute E, Orfao A et al. (1995) Proposals for the immunological classification of acute leukemias. European Group fo the immunological characterization of leukemia (EGIL) Leukemia 9:1783–1786

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Hematology, All India Institute of Medical Sciences, New Delhi, India

    Renu Saxena & Hema Anand

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  1. Renu Saxena
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  2. Hema Anand
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Correspondence to Renu Saxena.

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Saxena, R., Anand, H. Flow cytometry in acute leukemia. Indian J Hematol Blood Transfus 24, 146–150 (2008). https://doi.org/10.1007/s12288-008-0037-4

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  • DOI: https://doi.org/10.1007/s12288-008-0037-4

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